| ARK Investment Management LLC | Institution | 12.133.433 | 12,19% | US$ 398,46M | 2026-03-31 |
| FMR LLC | Institution | 11.310.905 | 11,36% | US$ 371,45M | 2026-03-31 |
| Farallon Capital Management, L.L.C. | Institution | 10.134.696 | 10,18% | US$ 332,82M | 2026-03-31 |
| BlackRock, Inc. | Institution | 8.487.494 | 8,53% | US$ 278,73M | 2026-03-31 |
| Farallon Healthcare Partners Master, L.P. | Institution | 6.023.589 | 6,05% | US$ 197,81M | 2025-12-31 |
| State Street Global Advisors, Inc. | Institution | 5.699.265 | 5,73% | US$ 187,16M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 4.570.797 | 4,59% | US$ 150,10M | 2026-03-31 |
| Arch Venture Partners, L.P. | Institution | 4.540.132 | 4,56% | US$ 149,10M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 4.377.374 | 4,40% | US$ 143,75M | 2026-03-31 |
| Amova Asset Management Co., Ltd. | Institution | 3.825.585 | 3,84% | US$ 125,63M | 2026-03-31 |
| Kynam Capital Management, LP | Institution | 3.682.185 | 3,70% | US$ 120,92M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 2.713.230 | 2,73% | US$ 89,10M | 2026-03-31 |
| UBS Asset Management AG | Institution | 2.479.775 | 2,49% | US$ 81,44M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 2.418.592 | 2,43% | US$ 79,43M | 2026-03-31 |
| ARCH Venture Partners IX LP | Institution | 2.270.067 | 2,28% | US$ 74,55M | 2025-03-31 |
| Arch Venture Fund IX Overage, L.P. | Institution | 2.270.067 | 2,28% | US$ 74,55M | 2025-03-31 |
| Mwg Management Ltd. | Institution | 2.266.934 | 2,28% | US$ 74,45M | 2025-09-30 |
| Dimensional Fund Advisors LP | Institution | 2.154.575 | 2,16% | US$ 70,76M | 2026-03-31 |
| Farallon Capital Offshore Investors II, L.P | Institution | 1.632.718 | 1,64% | US$ 53,62M | 2025-12-31 |
| ADAR1 Capital Management, LLC | Institution | 1.446.375 | 1,45% | US$ 47,50M | 2026-03-31 |
| Casdin Capital, LLC | Institution | 1.350.000 | 1,36% | US$ 44,33M | 2026-03-31 |
| Mwg Caph Ltd | Institution | 1.266.934 | 1,27% | US$ 41,61M | 2025-12-31 |
| Redmile Group, LLC | Institution | 1.237.659 | 1,24% | US$ 40,64M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 1.210.853 | 1,22% | US$ 39,76M | 2026-03-31 |
| Impresa Management LLC | Institution | 1.139.443 | 1,14% | US$ 37,42M | 2026-03-31 |
| F-Prime Capital Partners Healthcare Fund V LP | Institution | 1.139.443 | 1,14% | US$ 37,42M | 2025-03-31 |
| Qube Research & Technologies Ltd | Institution | 1.084.768 | 1,09% | US$ 35,62M | 2026-03-31 |
| Mr. John Evans | Insider | 949.267 | 0,95% | US$ 31,17M | 2026-04-01 |
| Farallon Capital Institutional Partners, L.P. | Institution | 836.691 | 0,84% | US$ 27,48M | 2025-12-31 |
| Northern Trust Global Investments | Institution | 825.580 | 0,83% | US$ 27,11M | 2026-03-31 |
| Deep Track Capital, LP | Institution | 820.765 | 0,82% | US$ 26,95M | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 808.436 | 0,81% | US$ 26,55M | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 700.647 | 0,70% | US$ 23,01M | 2026-03-31 |