| ARK Investment Management LLC | Institution | 12.133.433 | 12,19% | US$ 422,36M | 2026-03-31 |
| FMR LLC | Institution | 11.310.905 | 11,36% | US$ 393,73M | 2026-03-31 |
| Farallon Capital Management, L.L.C. | Institution | 10.134.696 | 10,18% | US$ 352,79M | 2026-03-31 |
| BlackRock, Inc. | Institution | 8.487.494 | 8,53% | US$ 295,45M | 2026-03-31 |
| Farallon Healthcare Partners Master, L.P. | Institution | 6.023.589 | 6,05% | US$ 209,68M | 2025-12-31 |
| State Street Global Advisors, Inc. | Institution | 5.699.265 | 5,73% | US$ 198,39M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 4.570.797 | 4,59% | US$ 159,11M | 2026-03-31 |
| Arch Venture Partners, L.P. | Institution | 4.540.132 | 4,56% | US$ 158,04M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 4.377.374 | 4,40% | US$ 152,38M | 2026-03-31 |
| Amova Asset Management Co., Ltd. | Institution | 3.825.585 | 3,84% | US$ 133,17M | 2026-03-31 |
| Kynam Capital Management, LP | Institution | 3.682.185 | 3,70% | US$ 128,18M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 2.713.230 | 2,73% | US$ 94,45M | 2026-03-31 |
| UBS Asset Management AG | Institution | 2.479.775 | 2,49% | US$ 86,32M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 2.418.592 | 2,43% | US$ 84,19M | 2026-03-31 |
| ARCH Venture Partners IX LP | Institution | 2.270.067 | 2,28% | US$ 79,02M | 2025-03-31 |
| Arch Venture Fund IX Overage, L.P. | Institution | 2.270.067 | 2,28% | US$ 79,02M | 2025-03-31 |
| Mwg Management Ltd. | Institution | 2.266.934 | 2,28% | US$ 78,91M | 2025-09-30 |
| Dimensional Fund Advisors LP | Institution | 2.154.575 | 2,16% | US$ 75,00M | 2026-03-31 |
| Farallon Capital Offshore Investors II, L.P | Institution | 1.632.718 | 1,64% | US$ 56,83M | 2025-12-31 |
| ADAR1 Capital Management, LLC | Institution | 1.446.375 | 1,45% | US$ 50,35M | 2026-03-31 |
| Casdin Capital, LLC | Institution | 1.350.000 | 1,36% | US$ 46,99M | 2026-03-31 |
| Mwg Caph Ltd | Institution | 1.266.934 | 1,27% | US$ 44,10M | 2025-12-31 |
| Redmile Group, LLC | Institution | 1.237.659 | 1,24% | US$ 43,08M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 1.210.853 | 1,22% | US$ 42,15M | 2026-03-31 |
| Impresa Management LLC | Institution | 1.139.443 | 1,14% | US$ 39,66M | 2026-03-31 |
| F-Prime Capital Partners Healthcare Fund V LP | Institution | 1.139.443 | 1,14% | US$ 39,66M | 2025-03-31 |
| Qube Research & Technologies Ltd | Institution | 1.084.768 | 1,09% | US$ 37,76M | 2026-03-31 |
| Farallon Capital Institutional Partners, L.P. | Institution | 836.691 | 0,84% | US$ 29,13M | 2025-12-31 |
| Northern Trust Global Investments | Institution | 825.580 | 0,83% | US$ 28,74M | 2026-03-31 |
| Deep Track Capital, LP | Institution | 820.765 | 0,82% | US$ 28,57M | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 808.436 | 0,81% | US$ 28,14M | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 700.647 | 0,70% | US$ 24,39M | 2026-03-31 |
| Farallon Capital Partners, L.P. | Institution | 688.623 | 0,69% | US$ 23,97M | 2025-12-31 |