| Baker Brothers Life Sciences, L.P. | Institution | 30.356.101 | 43,48% | US$ 127,80M | 2026-01-02 |
| Baker Bros. Advisors LP | Institution | 30.323.301 | 43,44% | US$ 127,66M | 2026-03-31 |
| Forbion Capital Partners B.V. | Institution | 3.468.430 | 4,97% | US$ 14,60M | 2026-03-31 |
| Armistice Capital LLC | Institution | 3.398.000 | 4,87% | US$ 14,31M | 2026-03-31 |
| Long Focus Capital Management LLC | Institution | 3.310.687 | 4,74% | US$ 13,94M | 2026-03-31 |
| Deep Track Biotechnology Master Fund, Ltd | Institution | 2.821.171 | 4,04% | US$ 11,88M | 2025-03-31 |
| Acadian Asset Management LLC | Institution | 1.968.025 | 2,82% | US$ 8,29M | 2026-03-31 |
| Artal Group S.A. | Institution | 1.560.882 | 2,24% | US$ 6,57M | 2026-03-31 |
| GSK Equity Investments, Limited | Institution | 1.529.561 | 2,19% | US$ 6,44M | 2026-03-31 |
| Invus Public Equities, L.P. | Institution | 1.368.586 | 1,96% | US$ 5,76M | 2026-03-31 |
| Principal Global Investors, LLC | Institution | 1.174.625 | 1,68% | US$ 4,95M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 1.028.243 | 1,47% | US$ 4,33M | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 979.300 | 1,40% | US$ 4,12M | 2026-03-31 |
| Morgan Stanley | Institution | 618.327 | 0,89% | US$ 2,60M | 2026-03-31 |
| Schroder Investment Management Limited | Institution | 615.833 | 0,88% | US$ 2,59M | 2026-03-31 |
| Dr. Kevin Lee | Insider | 598.811 | 0,86% | US$ 2,52M | 2026-04-06 |
| Diadema Partners LP | Institution | 476.424 | 0,68% | US$ 2,01M | 2026-03-31 |
| Birchview Capital, LP | Institution | 463.599 | 0,66% | US$ 1,95M | 2026-03-31 |
| Silvercrest Asset Management Group LLC | Institution | 428.684 | 0,61% | US$ 1,80M | 2026-03-31 |
| Marshall Wace LLP | Institution | 377.335 | 0,54% | US$ 1,59M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 377.085 | 0,54% | US$ 1,59M | 2026-03-31 |
| Medical Strategy GmbH | Institution | 343.416 | 0,49% | US$ 1,45M | 2025-06-30 |
| Qube Research & Technologies Ltd | Institution | 308.617 | 0,44% | US$ 1,30M | 2026-03-31 |
| Millennium Management LLC | Institution | 283.986 | 0,41% | US$ 1,20M | 2026-03-31 |
| BlackRock, Inc. | Institution | 278.992 | 0,40% | US$ 1,17M | 2026-03-31 |
| Moore Capital Management, LP | Institution | 275.000 | 0,39% | US$ 1,16M | 2026-03-31 |
| Bessemer Investment Management LLC | Institution | 265.973 | 0,38% | US$ 1,12M | 2026-01-30 |
| Rangeley Capital, LLC | Institution | 232.260 | 0,33% | US$ 977,81k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 218.115 | 0,31% | US$ 918,26k | 2026-03-31 |
| Palo Alto Investors LP | Institution | 201.890 | 0,29% | US$ 849,96k | 2026-03-31 |
| Avicenna Life Sci Master Fund Lp | Institution | 192.296 | 0,28% | US$ 809,57k | 2026-03-31 |
| Eversept Partners, L.P. | Institution | 190.715 | 0,27% | US$ 802,91k | 2026-03-31 |
| Pinnacle Associates, Ltd. | Institution | 185.410 | 0,27% | US$ 780,58k | 2026-03-31 |
| L1 Group Limited | Institution | 184.603 | 0,26% | US$ 777,18k | 2026-03-31 |
| Flax Pond Capital, LLC | Institution | 176.136 | 0,25% | US$ 741,53k | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 164.800 | 0,24% | US$ 693,81k | 2026-03-31 |
| Point72 Asset Management, L.P. | Institution | 130.422 | 0,19% | US$ 549,08k | 2026-03-31 |
| Manulife Asset Management | Institution | 127.863 | 0,18% | US$ 538,30k | 2026-03-31 |
| Peapod Lane Capital LLC | Institution | 121.106 | 0,17% | US$ 509,86k | 2026-03-31 |
| Persistent Asset Partners Limited | Institution | 120.437 | 0,17% | US$ 507,04k | 2026-03-31 |