| Vivo Capital, LLC | Institution | 3.153.640 | 8,76% | US$ 13,94M | 2026-03-31 |
| Vivo Opportunity Fund Holdings, L.P | Institution | 2.864.346 | 7,95% | US$ 12,66M | 2026-03-10 |
| Coastlands Capital LP | Institution | 2.815.900 | 7,82% | US$ 12,45M | 2025-05-28 |
| Adjuvant Capital, LP | Institution | 2.373.500 | 6,59% | US$ 10,49M | 2026-04-10 |
| Commodore Capital Master LP | Institution | 2.333.713 | 6,48% | US$ 10,32M | 2026-03-09 |
| Commodore Capital LP | Institution | 2.333.713 | 6,48% | US$ 10,32M | 2026-03-31 |
| Millennium Management LLC | Institution | 2.222.502 | 6,17% | US$ 9,82M | 2026-03-31 |
| Integrated Core Strategies (US) LLC | Institution | 2.135.044 | 5,93% | US$ 9,44M | 2026-03-06 |
| Adjuvant Global Health Technology Fund, L.P. | Institution | 1.995.958 | 5,54% | US$ 8,82M | 2026-04-10 |
| Spruce Street Capital LP | Institution | 1.661.073 | 4,61% | US$ 7,34M | 2026-03-31 |
| Almitas Capital LLC | Institution | 1.479.129 | 4,11% | US$ 6,54M | 2026-03-31 |
| Mr. Eric Easom | Insider | 1.321.512 | 3,67% | US$ 5,84M | 2026-02-20 |
| Mountain Group Capital, LLC | Institution | 1.234.861 | 3,43% | US$ 5,46M | 2025-03-24 |
| Vanguard Capital Management, LLC | Institution | 1.011.078 | 2,81% | US$ 4,47M | 2026-03-31 |
| Adage Capital Management, L.P. | Institution | 1.000.000 | 2,78% | US$ 4,42M | 2026-03-31 |
| Woodline Partners LP | Institution | 993.671 | 2,76% | US$ 4,39M | 2026-03-31 |
| Brii Biosciences Limited | Institution | 927.201 | 2,57% | US$ 4,10M | 2024-12-31 |
| Boxer Capital Management, LLC | Institution | 749.035 | 2,08% | US$ 3,31M | 2026-03-31 |
| Stonepine Capital Management LLC | Institution | 713.845 | 1,98% | US$ 3,16M | 2026-03-31 |
| Columbia Management Investment Advisers, LLC | Institution | 696.181 | 1,93% | US$ 3,08M | 2026-03-31 |
| Sio Capital Management, LLC | Institution | 657.200 | 1,82% | US$ 2,90M | 2026-03-31 |
| MGC Venture Partners QP 2018, L.P. | Institution | 652.573 | 1,81% | US$ 2,88M | 2025-03-24 |
| MGC Venture Partners 2018, L.P. | Institution | 582.288 | 1,62% | US$ 2,57M | 2025-03-24 |
| Mr. Joseph Zakrzewski | Insider | 551.418 | 1,53% | US$ 2,44M | 2025-04-10 |
| Ally Bridge Group | Institution | 526.315 | 1,46% | US$ 2,33M | 2026-03-31 |
| Prosight Management, LP | Institution | 515.754 | 1,43% | US$ 2,28M | 2026-03-31 |
| The Bank of Nova Scotia | Institution | 459.194 | 1,27% | US$ 2,03M | 2026-03-31 |
| BML Investment Partners, L.P. | Institution | 427.432 | 1,19% | US$ 1,89M | 2025-06-17 |
| Bank of America Corporation | Institution | 393.702 | 1,09% | US$ 1,74M | 2026-03-31 |
| Adjuvant Global Health Technology Fund DE, L.P. | Institution | 377.542 | 1,05% | US$ 1,67M | 2026-04-10 |
| Aldebaran Capital, LLC | Institution | 371.770 | 1,03% | US$ 1,64M | 2026-03-31 |
| BlackRock, Inc. | Institution | 318.768 | 0,89% | US$ 1,41M | 2026-03-31 |
| Jane Street Group, LLC | Institution | 303.649 | 0,84% | US$ 1,34M | 2026-03-31 |
| Landscape Capital Management, LLC | Institution | 298.166 | 0,83% | US$ 1,32M | 2026-03-31 |
| Vivo Opportunity Cayman Fund,L.P. | Institution | 289.294 | 0,80% | US$ 1,28M | 2026-03-10 |
| Geode Capital Management, LLC | Institution | 286.547 | 0,80% | US$ 1,27M | 2026-03-31 |
| BMO Asset Management Corp. | Institution | 260.127 | 0,72% | US$ 1,15M | 2026-03-31 |
| Morgan Stanley | Institution | 234.187 | 0,65% | US$ 1,04M | 2026-03-31 |
| Cantor Fitzgerald Asset Management | Institution | 200.000 | 0,56% | US$ 884,00k | 2026-03-31 |
| Seven Fleet Capital Management LP | Institution | 199.701 | 0,55% | US$ 882,68k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 198.800 | 0,55% | US$ 878,70k | 2026-03-31 |
| Citadel Advisors LLC | Institution | 155.239 | 0,43% | US$ 686,16k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 137.708 | 0,38% | US$ 608,67k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 115.202 | 0,32% | US$ 509,19k | 2026-03-31 |