| Qiming U.S. Healthcare Fund III, L.P. | Institution | 1.725.247 | 8,28% | $ 14,32M | 2026-03-31 |
| Qiming Weichuang Venture Capital Management (Shanghai) Company Limited | Institution | 1.725.247 | 8,28% | $ 14,32M | 2026-03-31 |
| Bloom Burton Investment Group Inc. | Institution | 1.010.167 | 4,85% | $ 8,38M | 2026-03-27 |
| Franklin Resources, Inc. | Institution | 938.666 | 4,51% | $ 7,79M | 2026-03-31 |
| Artal Group S.A. | Institution | 892.074 | 4,28% | $ 7,40M | 2026-03-31 |
| Vivo Capital, LLC | Institution | 813.666 | 3,91% | $ 6,75M | 2026-03-31 |
| Point72 Asset Management, L.P. | Institution | 690.778 | 3,32% | $ 5,73M | 2026-03-31 |
| Mr. Franklin Berger | Insider | 681.333 | 3,27% | $ 5,66M | 2026-03-27 |
| Woodline Partners LP | Institution | 500.432 | 2,40% | $ 4,15M | 2026-03-31 |
| Sphera Funds Management Ltd | Institution | 489.207 | 2,35% | $ 4,06M | 2026-03-31 |
| Suvretta Capital Management, LLC | Institution | 475.000 | 2,28% | $ 3,94M | 2026-03-31 |
| Soleus Capital Management, L.P. | Institution | 414.359 | 1,99% | $ 3,44M | 2026-03-31 |
| Avidity Partners Management, L.P. | Institution | 387.769 | 1,86% | $ 3,22M | 2026-03-31 |
| Adage Capital Management, L.P. | Institution | 380.354 | 1,83% | $ 3,16M | 2026-03-31 |
| Saturn V Capital Management LP | Institution | 350.000 | 1,68% | $ 2,91M | 2026-03-31 |
| Mr. Francis Gleeson | Insider | 331.365 | 1,59% | $ 2,75M | 2026-04-02 |
| Millennium Management LLC | Institution | 298.433 | 1,43% | $ 2,48M | 2026-03-31 |
| Dr. Michael Rudnicki | Insider | 258.159 | 1,24% | $ 2,14M | 2026-04-02 |
| 683 Capital Management, LLC | Institution | 230.833 | 1,11% | $ 1,92M | 2026-03-31 |
| Empery Asset Management, LP | Institution | 230.100 | 1,10% | $ 1,91M | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 222.555 | 1,07% | $ 1,85M | 2026-03-31 |
| AWM Investment Company Inc | Institution | 215.000 | 1,03% | $ 1,78M | 2026-03-31 |
| Mr. Brian Bloom | Insider | 123.233 | 0,59% | $ 1,02M | 2026-03-27 |
| Stonepine Capital Management LLC | Institution | 100.000 | 0,48% | $ 830,00k | 2026-03-31 |
| Citadel Advisors LLC | Institution | 42.492 | 0,20% | $ 352,68k | 2026-03-31 |
| Hudson River Trading LLC | Institution | 30.461 | 0,15% | $ 252,83k | 2026-03-31 |
| Mr. Mark Nawacki | Insider | 25.000 | 0,12% | $ 207,50k | 2026-04-07 |
| Mr. Geoff MacKay | Insider | 21.201 | 0,10% | $ 175,97k | 2026-03-27 |
| Morgan Stanley | Institution | 21.183 | 0,10% | $ 175,82k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 19.608 | 0,09% | $ 162,75k | 2026-03-31 |
| RBC Dominion Securities Inc. | Institution | 16.245 | 0,08% | $ 134,83k | 2026-03-31 |
| Monashee Investment Management, LLC | Institution | 12.000 | 0,06% | $ 99,60k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 11.907 | 0,06% | $ 98,83k | 2026-03-31 |
| Propel Bio Management, LLC | Institution | 10.145 | 0,05% | $ 84,20k | 2026-03-31 |
| AXQ Capital, LP | Institution | 10.096 | 0,05% | $ 83,80k | 2026-03-31 |
| China Universal Asset Management Company Ltd. | Institution | 6.400 | 0,03% | $ 53,12k | 2026-03-31 |
| Ms. Elizabeth Williams | Insider | 3.333 | 0,02% | $ 27,66k | 2026-04-02 |
| National Bank Investments Inc. | Institution | 2.115 | 0,01% | $ 17,55k | 2026-03-31 |
| MAI Capital Management, LLC | Institution | 140 | 0,00% | $ 1,16k | 2026-03-31 |
| UBS Asset Management AG | Institution | 28 | 0,00% | $ 232,40 | 2026-03-31 |
| Fédération des caisses Desjardins du Québec | Institution | 19 | 0,00% | $ 157,70 | 2026-03-31 |
| Caitong International Asset Management Co., Limited | Institution | 1 | 0,00% | $ 8,30 | 2026-03-31 |