| FMR LLC | Institution | 4.303.156 | 12,74% | 234,52M € | 2026-03-31 |
| BVF Partners L.P. | Institution | 2.559.595 | 7,58% | 139,50M € | 2026-03-31 |
| Two Seas Capital LP | Institution | 1.959.178 | 5,80% | 106,78M € | 2026-03-31 |
| Two Seas Global (Master) Fund Lp | Institution | 1.959.178 | 5,80% | 106,78M € | 2026-03-31 |
| Biotechnology Value Fund L.P. | Institution | 1.365.482 | 4,04% | 74,42M € | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.197.055 | 3,54% | 65,24M € | 2026-03-31 |
| Biotechnology Value Fund II, L.P. | Institution | 997.300 | 2,95% | 54,35M € | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 930.741 | 2,75% | 50,73M € | 2026-03-31 |
| Prosight Management, LP | Institution | 735.000 | 2,18% | 40,06M € | 2026-03-31 |
| BlackRock, Inc. | Institution | 692.650 | 2,05% | 37,75M € | 2026-03-31 |
| Emerald Advisers, LLC | Institution | 650.710 | 1,93% | 35,46M € | 2026-03-31 |
| Morgan Stanley | Institution | 637.935 | 1,89% | 34,77M € | 2026-03-31 |
| Armistice Capital LLC | Institution | 578.000 | 1,71% | 31,50M € | 2026-03-31 |
| Citadel Advisors LLC | Institution | 513.531 | 1,52% | 27,99M € | 2026-03-31 |
| Sofinnova Investments, Inc. | Institution | 509.546 | 1,51% | 27,77M € | 2026-03-31 |
| Invesco Ltd. | Institution | 425.341 | 1,26% | 23,18M € | 2026-03-31 |
| Woodline Partners LP | Institution | 415.335 | 1,23% | 22,64M € | 2026-03-31 |
| Lord, Abbett & Co. LLC | Institution | 405.080 | 1,20% | 22,08M € | 2026-03-31 |
| Millennium Management LLC | Institution | 404.277 | 1,20% | 22,03M € | 2026-03-31 |
| Qube Research & Technologies Ltd | Institution | 390.675 | 1,16% | 21,29M € | 2026-03-31 |
| UBS Asset Management AG | Institution | 354.197 | 1,05% | 19,30M € | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 346.795 | 1,03% | 18,90M € | 2026-03-31 |
| Integrated Core Strategies (US) LLC | Institution | 333.576 | 0,99% | 18,18M € | 2025-09-30 |
| Great Point Partners, LLC | Institution | 316.453 | 0,94% | 17,25M € | 2026-03-31 |
| Vestal Point Capital, LP | Institution | 285.000 | 0,84% | 15,53M € | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 283.617 | 0,84% | 15,46M € | 2026-03-31 |
| 22NW, LP | Institution | 281.115 | 0,83% | 15,32M € | 2026-03-31 |
| PRIMECAP Management Company | Institution | 279.150 | 0,83% | 15,21M € | 2026-03-31 |
| OrbiMed Advisors LLC | Institution | 275.000 | 0,81% | 14,99M € | 2026-03-31 |
| Gilder Gagnon Howe & Co. LLC | Institution | 271.758 | 0,80% | 14,81M € | 2026-03-31 |
| Nearwater Capital Markets, Limited | Institution | 261.500 | 0,77% | 14,25M € | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 244.727 | 0,72% | 13,34M € | 2026-03-31 |
| JPMorgan Chase & Co. | Institution | 240.101 | 0,71% | 13,09M € | 2026-03-31 |
| Braidwell LP | Institution | 222.701 | 0,66% | 12,14M € | 2026-03-31 |
| Patient Square Capital, LP | Institution | 210.000 | 0,62% | 11,45M € | 2026-03-31 |
| Bronte Capital Management Pty Ltd | Institution | 198.256 | 0,59% | 10,80M € | 2026-03-31 |
| Quinn Opportunity Partners LLC | Institution | 179.247 | 0,53% | 9,77M € | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 169.308 | 0,50% | 9,23M € | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 168.007 | 0,50% | 9,16M € | 2026-03-31 |
| Dafna Capital Management, LLC | Institution | 165.178 | 0,49% | 9,00M € | 2026-03-31 |