| Farallon Capital Management, L.L.C. | Institution | 13.604.796 | 6,40% | 2,27B € | 2026-03-31 |
| BlackRock, Inc. | Institution | 11.212.706 | 5,27% | 1,87B € | 2026-03-31 |
| Janus Henderson Group plc | Institution | 9.766.496 | 4,59% | 1,63B € | 2026-03-31 |
| Baker Bros. Advisors LP | Institution | 9.555.357 | 4,49% | 1,60B € | 2026-03-31 |
| FMR LLC | Institution | 8.452.363 | 3,98% | 1,41B € | 2026-03-31 |
| Farallon Healthcare Partners Master, L.P. | Institution | 8.420.065 | 3,96% | 1,41B € | 2025-12-31 |
| Vanguard Capital Management, LLC | Institution | 8.362.284 | 3,93% | 1,40B € | 2026-03-31 |
| Nextech Invest Ltd. | Institution | 7.601.087 | 3,58% | 1,27B € | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 7.502.623 | 3,53% | 1,25B € | 2026-03-31 |
| Paradigm Biocapital Advisors LP | Institution | 6.655.703 | 3,13% | 1,11B € | 2026-03-31 |
| Wellington Management Group LLP | Institution | 6.027.819 | 2,84% | 1,01B € | 2026-03-31 |
| Adage Capital Management, L.P. | Institution | 5.475.611 | 2,58% | 914,43M € | 2026-03-31 |
| UBS Asset Management AG | Institution | 4.887.386 | 2,30% | 816,19M € | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 4.402.662 | 2,07% | 735,24M € | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 3.896.260 | 1,83% | 650,68M € | 2026-03-31 |
| Nextech V Oncology S.C.S., SICAV-SIF | Institution | 3.590.313 | 1,69% | 599,58M € | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 3.338.142 | 1,57% | 557,47M € | 2026-03-31 |
| GV Management Company, LLC | Institution | 3.292.525 | 1,55% | 549,85M € | 2026-03-31 |
| BVF Partners L.P. | Institution | 2.856.782 | 1,34% | 477,08M € | 2026-03-31 |
| Casdin Capital, LLC | Institution | 2.577.333 | 1,21% | 430,41M € | 2026-03-31 |
| Woodline Partners LP | Institution | 2.506.570 | 1,18% | 418,60M € | 2026-03-31 |
| Farallon Capital Offshore Investors II, L.P | Institution | 2.482.796 | 1,17% | 414,63M € | 2025-12-31 |
| Holocene Advisors, LP | Institution | 2.468.644 | 1,16% | 412,26M € | 2026-03-31 |
| Norges Bank Investment Management | Institution | 2.455.347 | 1,15% | 410,04M € | 2025-12-31 |
| Vestal Point Capital, LP | Institution | 2.375.000 | 1,12% | 396,63M € | 2026-03-31 |
| Avoro Capital Advisors LLC | Institution | 2.344.444 | 1,10% | 391,52M € | 2026-03-31 |
| Mr. Alexis Borisy | Insider | 2.338.884 | 1,10% | 390,59M € | 2026-06-18 |
| Deerfield Management Company, L.P. | Institution | 2.297.000 | 1,08% | 383,60M € | 2026-03-31 |
| Darwin Global Management Limited | Institution | 2.211.018 | 1,04% | 369,24M € | 2026-03-31 |
| Logos Global Management, L.P. | Institution | 2.000.000 | 0,94% | 334,00M € | 2026-03-31 |
| Alyeska Investment Group, L.P. | Institution | 1.885.821 | 0,89% | 314,93M € | 2026-03-31 |
| National Bank Investments Inc. | Institution | 1.749.000 | 0,82% | 292,08M € | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 1.735.476 | 0,82% | 289,82M € | 2026-03-31 |
| Caligan Partners, LP | Institution | 1.652.808 | 0,78% | 276,02M € | 2026-03-31 |
| Columbia Management Investment Advisers, LLC | Institution | 1.579.793 | 0,74% | 263,83M € | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 1.560.805 | 0,73% | 260,65M € | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 1.558.807 | 0,73% | 260,32M € | 2026-03-31 |
| Westfield Capital Management Company, L.P. | Institution | 1.556.578 | 0,73% | 259,95M € | 2026-03-31 |
| Bellevue Asset Management AG | Institution | 1.544.456 | 0,73% | 257,92M € | 2026-03-31 |
| Integral Health Asset Management, LLC | Institution | 1.500.000 | 0,71% | 250,50M € | 2026-03-31 |
| Farallon Capital Institutional Partners, L.P. | Institution | 1.377.579 | 0,65% | 230,06M € | 2025-12-31 |