| BlackRock, Inc. | Institution | 14.207.702 | 7,25% | 832,86M € | 2026-03-31 |
| KKR Genetic Disorder L.P. | Institution | 13.260.971 | 6,77% | 777,36M € | 2025-05-12 |
| KKR & Co. Inc. | Institution | 13.260.971 | 6,77% | 777,36M € | 2026-03-31 |
| Janus Henderson Group plc | Institution | 13.179.013 | 6,73% | 772,55M € | 2026-03-31 |
| Viking Global Investors LP | Institution | 11.842.434 | 6,05% | 694,20M € | 2026-03-31 |
| VGO Illiquid Investments Sub-Master LP | Institution | 11.842.434 | 6,05% | 694,20M € | 2026-03-31 |
| Farallon Capital Management, L.L.C. | Institution | 10.226.063 | 5,22% | 599,45M € | 2026-05-22 |
| Vanguard Portfolio Management, LLC | Institution | 8.080.573 | 4,13% | 473,68M € | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 7.759.495 | 3,96% | 454,86M € | 2026-03-31 |
| Farallon Healthcare Partners Master, L.P. | Institution | 5.918.914 | 3,02% | 346,97M € | 2026-05-22 |
| Dr. Neil Kumar | Insider | 5.157.460 | 2,63% | 302,33M € | 2026-05-21 |
| Aisling Capital Management LP | Institution | 5.089.611 | 2,60% | 298,35M € | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 4.934.320 | 2,52% | 289,25M € | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 4.918.030 | 2,51% | 288,29M € | 2026-03-31 |
| Invesco Ltd. | Institution | 4.435.675 | 2,26% | 260,02M € | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 3.801.655 | 1,94% | 222,85M € | 2026-03-31 |
| Frazier Life Sciences Management, LP | Institution | 3.448.139 | 1,76% | 202,13M € | 2026-03-31 |
| Citadel Advisors LLC | Institution | 3.173.940 | 1,62% | 186,06M € | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 3.120.631 | 1,59% | 182,93M € | 2026-03-31 |
| D. E. Shaw & Co., L.P. | Institution | 2.545.486 | 1,30% | 149,22M € | 2026-03-31 |
| Polar Capital Holdings Plc | Institution | 2.519.306 | 1,29% | 147,68M € | 2026-03-31 |
| Wellington Management Group LLP | Institution | 2.483.953 | 1,27% | 145,61M € | 2026-03-31 |
| UBS Asset Management AG | Institution | 2.429.769 | 1,24% | 142,43M € | 2026-03-31 |
| FMR LLC | Institution | 2.336.028 | 1,19% | 136,94M € | 2026-03-31 |
| Manulife Asset Management | Institution | 1.977.080 | 1,01% | 115,90M € | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 1.976.094 | 1,01% | 115,84M € | 2026-03-31 |
| AllianceBernstein L.P. | Institution | 1.908.907 | 0,97% | 111,90M € | 2026-03-31 |
| Farallon Capital Offshore Investors II, L.P | Institution | 1.869.577 | 0,95% | 109,59M € | 2026-05-22 |
| Sequoia Capital Operations LLC | Institution | 1.860.364 | 0,95% | 109,05M € | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 1.767.469 | 0,90% | 103,61M € | 2026-03-31 |
| Jane Street Group, LLC | Institution | 1.757.672 | 0,90% | 103,03M € | 2026-03-31 |
| Nomura Investment Management Business Trust | Institution | 1.534.736 | 0,78% | 89,97M € | 2026-03-31 |
| Norges Bank Investment Management | Institution | 1.527.028 | 0,78% | 89,51M € | 2025-12-31 |
| Northern Trust Global Investments | Institution | 1.403.642 | 0,72% | 82,28M € | 2026-03-31 |
| Morgan Stanley | Institution | 1.402.191 | 0,72% | 82,20M € | 2026-03-31 |
| Pictet Asset Management Limited | Institution | 1.381.184 | 0,71% | 80,97M € | 2026-03-31 |
| Principal Global Investors, LLC | Institution | 1.330.415 | 0,68% | 77,99M € | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 1.307.176 | 0,67% | 76,63M € | 2026-03-31 |