| Gilead Sciences, Inc. | Institution | 650.389 | 10,87% | US$ 6,23M | 2026-03-31 |
| Ms. Yekaterina Chudnovsky | Insider | 500.000 | 8,36% | US$ 4,79M | 2026-01-02 |
| Frazier Life Sciences Management, LP | Institution | 422.505 | 7,06% | US$ 4,05M | 2026-03-31 |
| Frazier Life Sciences Public Fund, L.P. | Institution | 334.034 | 5,58% | US$ 3,20M | 2025-12-31 |
| AbbVie Inc. | Institution | 310.559 | 5,19% | US$ 2,98M | 2026-01-02 |
| Coastlands Capital LP | Institution | 309.442 | 5,17% | US$ 2,96M | 2025-12-04 |
| Coastlands Capital Partners LP | Institution | 309.442 | 5,17% | US$ 2,96M | 2025-12-04 |
| Sirenia Capital Management LP | Institution | 285.714 | 4,78% | US$ 2,74M | 2026-03-31 |
| Point72 Associates, LLC | Institution | 285.714 | 4,78% | US$ 2,74M | 2026-01-02 |
| Sio Capital Management, LLC | Institution | 152.464 | 2,55% | US$ 1,46M | 2026-03-31 |
| StemPoint Capital Master Fund LP | Institution | 142.857 | 2,39% | US$ 1,37M | 2026-01-02 |
| Vanguard Capital Management, LLC | Institution | 123.660 | 2,07% | US$ 1,18M | 2026-03-31 |
| Caligan Partners, LP | Institution | 112.128 | 1,87% | US$ 1,07M | 2026-03-31 |
| MRL Ventures Fund LLC | Institution | 105.982 | 1,77% | US$ 1,02M | 2026-03-31 |
| Takeda Pharmaceutical Company Limited | Institution | 105.365 | 1,76% | US$ 1,01M | 2025-09-30 |
| Stonepine Capital Management LLC | Institution | 64.162 | 1,07% | US$ 614,67k | 2026-03-31 |
| Morgan Stanley | Institution | 57.493 | 0,96% | US$ 550,78k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 49.566 | 0,83% | US$ 474,84k | 2026-03-31 |
| Frazier Life Sciences XII, L.P. | Institution | 49.476 | 0,83% | US$ 473,98k | 2025-12-31 |
| AJU IB INVESTMENT Co., Ltd. | Institution | 47.695 | 0,80% | US$ 456,92k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 37.197 | 0,62% | US$ 356,35k | 2026-03-31 |
| Impresa Management LLC | Institution | 36.558 | 0,61% | US$ 350,23k | 2026-03-31 |
| Four Pines Master Fund LP | Institution | 28.760 | 0,48% | US$ 275,52k | 2024-09-30 |
| Vanguard Fiduciary Trust Company | Institution | 28.475 | 0,48% | US$ 272,79k | 2026-03-31 |
| Frazier Life Sciences XI, L.P. | Institution | 28.350 | 0,47% | US$ 271,59k | 2025-12-31 |
| Dr. Rene Russo | Insider | 23.242 | 0,39% | US$ 222,66k | 2026-04-15 |
| GSA Capital Partners LLP | Institution | 16.946 | 0,28% | US$ 162,34k | 2026-03-31 |
| Velan Capital Partners LP | Institution | 14.285 | 0,24% | US$ 136,85k | 2026-03-31 |
| Ghisallo Capital Management LLC | Institution | 13.800 | 0,23% | US$ 132,20k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 13.311 | 0,22% | US$ 127,52k | 2026-03-31 |
| Frazier Life Sciences X, L.P. | Institution | 10.647 | 0,18% | US$ 102,00k | 2025-12-31 |
| Carson Wealth Management Group | Institution | 4.206 | 0,07% | US$ 40,29k | 2026-03-31 |
| UBS Asset Management AG | Institution | 4.038 | 0,07% | US$ 38,68k | 2026-03-31 |
| Dr. Katarina Luptakova | Insider | 2.374 | 0,04% | US$ 22,74k | 2026-04-15 |
| Mr. Christopher Frankenfield | Insider | 1.768 | 0,03% | US$ 16,94k | 2026-04-15 |
| Mr. Kevin Brennan | Insider | 455 | 0,01% | US$ 4,36k | 2026-01-02 |
| JPMorgan Chase & Co. | Institution | 240 | 0,00% | US$ 2,30k | 2026-03-31 |
| Vanguard Global Advisers, LLC | Institution | 210 | 0,00% | US$ 2,01k | 2026-03-31 |
| Royal Bank of Canada | Institution | 91 | 0,00% | US$ 871,78 | 2026-03-31 |
| Key Financial, Inc. | Institution | 59 | 0,00% | US$ 565,22 | 2026-03-31 |