| Madryn Asset Management, LP | Institution | 18.475.893 | 26,55% | US$ 24,02M | 2026-03-31 |
| Madryn Health Partners Ii (Cayman Master), Lp | Institution | 17.044.940 | 24,49% | US$ 22,16M | 2026-03-02 |
| Parian Global Management LP | Institution | 4.844.908 | 6,96% | US$ 6,30M | 2026-03-17 |
| UBS Asset Management AG | Institution | 2.870.598 | 4,13% | US$ 3,73M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 2.743.768 | 3,94% | US$ 3,57M | 2026-03-31 |
| BlackRock, Inc. | Institution | 2.318.537 | 3,33% | US$ 3,01M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 2.047.975 | 2,94% | US$ 2,66M | 2026-03-31 |
| Lane Generational LLC | Institution | 1.774.624 | 2,55% | US$ 2,31M | 2026-03-31 |
| FourWorld Capital Management LLC | Institution | 1.489.322 | 2,14% | US$ 1,94M | 2026-03-31 |
| Masters Capital Management, L.L.C. | Institution | 1.000.000 | 1,44% | US$ 1,30M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 958.989 | 1,38% | US$ 1,25M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 842.547 | 1,21% | US$ 1,10M | 2026-03-31 |
| Ikarian Capital, LLC | Institution | 701.182 | 1,01% | US$ 911,54k | 2026-03-31 |
| Wexford Capital LP | Institution | 700.961 | 1,01% | US$ 911,25k | 2026-03-31 |
| AdvisorShares Investments, LLC | Institution | 617.193 | 0,89% | US$ 802,35k | 2026-03-31 |
| HighTower Advisors, LLC | Institution | 562.370 | 0,81% | US$ 731,08k | 2026-03-31 |
| Northern Trust Global Investments | Institution | 277.378 | 0,40% | US$ 360,59k | 2026-03-31 |
| Dauntless Investment Group, Llc | Institution | 269.208 | 0,39% | US$ 349,97k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 258.034 | 0,37% | US$ 335,44k | 2026-03-31 |
| JBF Capital, Inc. | Institution | 233.166 | 0,34% | US$ 303,12k | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 221.170 | 0,32% | US$ 287,52k | 2026-03-31 |
| Massar Capital Management, LP | Institution | 221.000 | 0,32% | US$ 287,30k | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 189.263 | 0,27% | US$ 246,04k | 2026-03-31 |
| Goldman Sachs Asset Management, L.P. | Institution | 185.832 | 0,27% | US$ 241,58k | 2026-03-31 |
| Centiva Capital, LP | Institution | 169.319 | 0,24% | US$ 220,11k | 2026-03-31 |
| XTX Markets Limited | Institution | 146.155 | 0,21% | US$ 190,00k | 2026-03-31 |
| GAMCO Investors, Inc. | Institution | 117.200 | 0,17% | US$ 152,36k | 2026-03-31 |
| Arrow Capital Management Inc. | Institution | 114.940 | 0,17% | US$ 149,42k | 2025-12-31 |
| Clarfeld Financial Advisors, LLC | Institution | 110.953 | 0,16% | US$ 144,24k | 2026-03-31 |
| AQR Capital Management, LLC | Institution | 107.570 | 0,15% | US$ 139,84k | 2026-03-31 |
| Hudson River Trading LLC | Institution | 100.620 | 0,14% | US$ 130,81k | 2026-03-31 |
| VestGen Advisors, LLC | Institution | 100.413 | 0,14% | US$ 130,54k | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 100.000 | 0,14% | US$ 130,00k | 2026-03-31 |
| Bank of America Corporation | Institution | 98.095 | 0,14% | US$ 127,52k | 2026-03-31 |
| Bridgeway Capital Management, LLC | Institution | 95.205 | 0,14% | US$ 123,77k | 2026-03-31 |
| RBC Dominion Securities Inc. | Institution | 88.773 | 0,13% | US$ 115,40k | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 86.481 | 0,12% | US$ 112,43k | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 82.123 | 0,12% | US$ 106,76k | 2026-03-31 |