| Ikarian Capital, LLC | Institution | 121.356 | 4,49% | US$ 5,98M | 2026-04-30 |
| Ikarian Healthcare Master Fund, L.P. | Institution | 121.356 | 4,49% | US$ 5,98M | 2026-04-30 |
| Millennium Management LLC | Institution | 111.888 | 4,14% | US$ 5,52M | 2026-03-31 |
| Integrated Core Strategies (US) LLC | Institution | 103.026 | 3,81% | US$ 5,08M | 2026-03-24 |
| Citadel Advisors LLC | Institution | 70.065 | 2,59% | US$ 3,45M | 2026-03-31 |
| Squadron Master Fund LP | Institution | 70.000 | 2,59% | US$ 3,45M | 2026-03-24 |
| Peter Boone | Insider | 68.184 | 2,52% | US$ 3,36M | 2025-11-21 |
| ADAR1 Capital Management, LLC | Institution | 58.600 | 2,17% | US$ 2,89M | 2026-03-31 |
| Alyeska Investment Group, L.P. | Institution | 51.671 | 1,91% | US$ 2,55M | 2026-03-31 |
| Wellington Management Group LLP | Institution | 48.796 | 1,81% | US$ 2,41M | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 42.080 | 1,56% | US$ 2,07M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 40.000 | 1,48% | US$ 1,97M | 2026-03-31 |
| Abingworth LLP | Institution | 38.620 | 1,43% | US$ 1,90M | 2026-03-31 |
| Abingworth Bioventures VII LP | Institution | 38.620 | 1,43% | US$ 1,90M | 2026-02-18 |
| Armistice Capital LLC | Institution | 28.923 | 1,07% | US$ 1,43M | 2025-04-01 |
| Armistice Capital Master Fund Ltd. | Institution | 28.923 | 1,07% | US$ 1,43M | 2025-04-01 |
| Odlander, Fredrikson & Co. AB | Institution | 27.201 | 1,01% | US$ 1,34M | 2025-10-07 |
| HealthCap VIII, L.P. | Institution | 27.201 | 1,01% | US$ 1,34M | 2025-10-07 |
| Quinn Opportunity Partners LLC | Institution | 26.810 | 0,99% | US$ 1,32M | 2026-03-31 |
| ExodusPoint Capital Management, LP | Institution | 22.000 | 0,81% | US$ 1,08M | 2026-04-27 |
| Exoduspoint Partners Master Fund, LP | Institution | 22.000 | 0,81% | US$ 1,08M | 2026-04-27 |
| Dr. Javier Szwarcberg | Insider | 19.004 | 0,70% | US$ 936,90k | 2026-03-24 |
| Vanguard Capital Management, LLC | Institution | 18.337 | 0,68% | US$ 904,01k | 2026-03-31 |
| BlackRock, Inc. | Institution | 16.938 | 0,63% | US$ 835,04k | 2026-03-31 |
| RiverVest Venture Management LLC | Institution | 15.580 | 0,58% | US$ 768,09k | 2025-01-07 |
| Geode Capital Management, LLC | Institution | 12.889 | 0,48% | US$ 635,43k | 2026-03-31 |
| Squadron Capital Management Llc | Institution | 12.200 | 0,45% | US$ 601,46k | 2026-03-31 |
| Diadema Partners LP | Institution | 10.000 | 0,37% | US$ 493,00k | 2026-03-31 |
| RiverVest Venture Fund III LP | Institution | 8.543 | 0,32% | US$ 421,17k | 2025-01-07 |
| Mr. Samir Gharib | Insider | 8.263 | 0,31% | US$ 407,37k | 2026-03-24 |
| Rivervest Venture Fund IV, L.P. | Institution | 7.038 | 0,26% | US$ 346,97k | 2025-01-07 |
| StemPoint Capital LP | Institution | 6.360 | 0,24% | US$ 313,55k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 5.514 | 0,20% | US$ 271,84k | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 5.506 | 0,20% | US$ 271,45k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 5.400 | 0,20% | US$ 266,22k | 2026-03-31 |
| Resolute Capital Asset Partners LLC | Institution | 4.000 | 0,15% | US$ 197,20k | 2026-03-31 |
| UBS Asset Management AG | Institution | 3.919 | 0,15% | US$ 193,21k | 2026-03-31 |
| Persistent Asset Partners Limited | Institution | 2.528 | 0,09% | US$ 124,63k | 2026-03-31 |
| Dr. Ralph Charlton | Insider | 2.151 | 0,08% | US$ 106,04k | 2025-04-01 |
| Morgan Stanley | Institution | 1.415 | 0,05% | US$ 69,76k | 2026-03-31 |
| Dr. Kirk Ways | Insider | 1.250 | 0,05% | US$ 61,63k | 2026-03-24 |