| RA Capital Management, L.P. | Institution | 9.905.045 | 21,94% | US$ 361,34M | 2026-03-31 |
| RA Capital Healthcare Fund, L.P. | Institution | 6.897.623 | 15,28% | US$ 251,63M | 2025-11-21 |
| TPG Capital, L.P. | Institution | 6.494.962 | 14,39% | US$ 236,94M | 2026-03-31 |
| Viking Global Investors LP | Institution | 3.195.181 | 7,08% | US$ 116,56M | 2026-03-31 |
| Atlas Venture Advisors, Inc. | Institution | 2.995.602 | 6,63% | US$ 109,28M | 2026-03-31 |
| Orbimed Private Investments VIII, LP | Institution | 2.671.822 | 5,92% | US$ 97,47M | 2026-05-11 |
| OrbiMed Advisors LLC | Institution | 2.671.822 | 5,92% | US$ 97,47M | 2026-05-11 |
| Enavate Sciences | Institution | 2.478.030 | 5,49% | US$ 90,40M | 2026-03-31 |
| Atlas Venture Fund XI, L.P. | Institution | 2.309.035 | 5,11% | US$ 84,23M | 2025-10-21 |
| RA Capital Nexus Fund III, L.P. | Institution | 2.198.082 | 4,87% | US$ 80,19M | 2025-11-21 |
| Qatar Holding LLC | Institution | 2.020.258 | 4,47% | US$ 73,70M | 2026-03-31 |
| Viking Global Opportunities Illiquid Investments Sub-Master LP | Institution | 1.894.346 | 4,20% | US$ 69,11M | 2025-02-10 |
| Jennison Associates LLC | Institution | 1.451.220 | 3,21% | US$ 52,94M | 2026-03-31 |
| JP Morgan Asset Management | Institution | 1.433.908 | 3,18% | US$ 52,31M | 2026-03-31 |
| BlackRock, Inc. | Institution | 1.295.859 | 2,87% | US$ 47,27M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 1.166.931 | 2,58% | US$ 42,57M | 2026-03-31 |
| Viking Global Opportunities Drawdown (Aggregator) LP | Institution | 1.058.408 | 2,34% | US$ 38,61M | 2025-02-10 |
| Vanguard Capital Management, LLC | Institution | 1.029.497 | 2,28% | US$ 37,56M | 2026-03-31 |
| Deerfield Management Company, L.P. | Institution | 970.590 | 2,15% | US$ 35,41M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 756.376 | 1,68% | US$ 27,59M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 756.227 | 1,67% | US$ 27,59M | 2026-03-31 |
| Atlas Venture Opportunity Fund II, L.P. | Institution | 686.567 | 1,52% | US$ 25,05M | 2025-10-21 |
| Perceptive Advisors LLC | Institution | 658.439 | 1,46% | US$ 24,02M | 2026-03-31 |
| RA Capital Nexus Fund, L.P. | Institution | 650.307 | 1,44% | US$ 23,72M | 2025-11-21 |
| Eventide Asset Management, LLC | Institution | 645.530 | 1,43% | US$ 23,55M | 2026-03-31 |
| Aberdeen Group Plc | Institution | 564.175 | 1,25% | US$ 20,58M | 2026-03-31 |
| Mr. Michael Cloonan | Insider | 547.343 | 1,21% | US$ 19,97M | 2025-10-21 |
| Baker Bros. Advisors LP | Institution | 400.000 | 0,89% | US$ 14,59M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 389.872 | 0,86% | US$ 14,22M | 2026-03-31 |
| Artal Group S.A. | Institution | 300.000 | 0,66% | US$ 10,94M | 2026-03-31 |
| Sio Capital Management, LLC | Institution | 294.340 | 0,65% | US$ 10,74M | 2026-03-31 |
| Soleus Capital Management, L.P. | Institution | 293.500 | 0,65% | US$ 10,71M | 2026-03-31 |
| Norges Bank Investment Management | Institution | 270.343 | 0,60% | US$ 9,86M | 2025-12-31 |
| Ensign Peak Advisors, Inc. | Institution | 255.636 | 0,57% | US$ 9,33M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 255.554 | 0,57% | US$ 9,32M | 2026-03-31 |
| Candriam, Société En Commandite Par Actions | Institution | 236.813 | 0,52% | US$ 8,64M | 2026-03-31 |
| Kalehua Capital Management LLC | Institution | 197.072 | 0,44% | US$ 7,19M | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 175.483 | 0,39% | US$ 6,40M | 2026-03-31 |