| Eli Lilly and Company | Institution | 16.895.100 | 16,04% | US$ 25,34M | 2025-12-31 |
| Van Herk Investments B.V. | Institution | 15.384.250 | 14,60% | US$ 23,08M | 2026-06-02 |
| Adage Capital Partners, L.P. | Institution | 6.601.938 | 6,27% | US$ 9,90M | 2025-06-30 |
| Adage Capital Management, L.P. | Institution | 6.253.467 | 5,94% | US$ 9,38M | 2026-03-31 |
| Privium Fund Management BV | Institution | 5.467.149 | 5,19% | US$ 8,20M | 2026-03-31 |
| Aberdeen Group Plc | Institution | 3.316.965 | 3,15% | US$ 4,98M | 2026-03-31 |
| Affinity Asset Advisors, LLC | Institution | 2.454.278 | 2,33% | US$ 3,68M | 2026-03-31 |
| Sio Capital Management, LLC | Institution | 1.954.715 | 1,86% | US$ 2,93M | 2026-03-31 |
| Dafna Capital Management, LLC | Institution | 1.567.561 | 1,49% | US$ 2,35M | 2026-03-31 |
| Kynam Capital Management, LP | Institution | 1.566.317 | 1,49% | US$ 2,35M | 2026-03-31 |
| Ikarian Capital, LLC | Institution | 1.492.229 | 1,42% | US$ 2,24M | 2026-03-31 |
| Morgan Stanley | Institution | 1.299.775 | 1,23% | US$ 1,95M | 2026-03-31 |
| L1 Group Limited | Institution | 1.235.514 | 1,17% | US$ 1,85M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 918.857 | 0,87% | US$ 1,38M | 2026-03-31 |
| Dr. Gerard Platenburg | Insider | 824.388 | 0,78% | US$ 1,24M | 2026-03-18 |
| Point72 Asset Management, L.P. | Institution | 755.842 | 0,72% | US$ 1,13M | 2026-03-31 |
| Dr. Domenico Valerio | Insider | 725.692 | 0,69% | US$ 1,09M | 2026-03-18 |
| Citadel Advisors LLC | Institution | 703.323 | 0,67% | US$ 1,05M | 2026-03-31 |
| Nomura Investment Management Business Trust | Institution | 620.000 | 0,59% | US$ 930,00k | 2026-03-31 |
| Walleye Capital LLC | Institution | 607.529 | 0,58% | US$ 911,29k | 2026-03-31 |
| M28 Capital Management LP | Institution | 599.793 | 0,57% | US$ 899,69k | 2026-03-31 |
| Raymond James Financial, Inc. | Institution | 546.079 | 0,52% | US$ 819,12k | 2026-03-31 |
| Mr. Rene Beukema | Insider | 460.000 | 0,44% | US$ 690,00k | 2025-12-31 |
| Monaco Asset Management S.A.M. | Institution | 418.803 | 0,40% | US$ 628,20k | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 355.283 | 0,34% | US$ 532,92k | 2026-03-31 |
| UBS Asset Management AG | Institution | 305.264 | 0,29% | US$ 457,90k | 2026-03-31 |
| Valerio Family Foundation | Institution | 304.963 | 0,29% | US$ 457,44k | 2025-12-31 |
| Northern Trust Global Investments | Institution | 291.314 | 0,28% | US$ 436,97k | 2026-03-31 |
| Medical Strategy GmbH | Institution | 240.453 | 0,23% | US$ 360,68k | 2025-12-31 |
| Millennium Management LLC | Institution | 194.246 | 0,18% | US$ 291,37k | 2026-03-31 |
| Palo Alto Investors LP | Institution | 188.807 | 0,18% | US$ 283,21k | 2026-03-31 |
| Bank of America Corporation | Institution | 185.110 | 0,18% | US$ 277,67k | 2026-03-31 |
| Diadema Partners LP | Institution | 180.083 | 0,17% | US$ 270,12k | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 172.349 | 0,16% | US$ 258,52k | 2026-03-31 |
| Franklin Street Advisors, Inc. | Institution | 150.000 | 0,14% | US$ 225,00k | 2026-03-31 |
| Marshall Wace LLP | Institution | 115.945 | 0,11% | US$ 173,92k | 2026-03-31 |
| GSA Capital Partners LLP | Institution | 114.256 | 0,11% | US$ 171,38k | 2026-03-31 |
| Deutsche Asset & Wealth Management | Institution | 108.762 | 0,10% | US$ 163,14k | 2026-03-31 |
| Graham Capital Management, L.P. | Institution | 91.553 | 0,09% | US$ 137,33k | 2026-03-31 |
| OneDigital Investment Advisors, LLC | Institution | 85.000 | 0,08% | US$ 127,50k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 84.909 | 0,08% | US$ 127,36k | 2026-03-31 |
| XTX Markets Limited | Institution | 77.287 | 0,07% | US$ 115,93k | 2026-03-31 |
| Lynx1 Capital Management LP | Institution | 68.486 | 0,07% | US$ 102,73k | 2026-03-31 |
| Dr. James Shannon | Insider | 61.538 | 0,06% | US$ 92,31k | 2026-03-18 |