| Van Herk Investments B.V. | Institution | 15.384.250 | 14,60% | US$ 26,92M | 2026-06-02 |
| Adage Capital Partners, L.P. | Institution | 6.601.938 | 6,27% | US$ 11,55M | 2025-06-30 |
| Adage Capital Management, L.P. | Institution | 6.253.467 | 5,94% | US$ 10,94M | 2026-03-31 |
| Privium Fund Management BV | Institution | 5.467.149 | 5,19% | US$ 9,57M | 2026-03-31 |
| Aberdeen Group Plc | Institution | 3.316.965 | 3,15% | US$ 5,80M | 2026-03-31 |
| Affinity Asset Advisors, LLC | Institution | 2.454.278 | 2,33% | US$ 4,29M | 2026-03-31 |
| Sio Capital Management, LLC | Institution | 1.954.715 | 1,86% | US$ 3,42M | 2026-03-31 |
| Dafna Capital Management, LLC | Institution | 1.567.561 | 1,49% | US$ 2,74M | 2026-03-31 |
| Kynam Capital Management, LP | Institution | 1.566.317 | 1,49% | US$ 2,74M | 2026-03-31 |
| Ikarian Capital, LLC | Institution | 1.492.229 | 1,42% | US$ 2,61M | 2026-03-31 |
| Morgan Stanley | Institution | 1.299.775 | 1,23% | US$ 2,27M | 2026-03-31 |
| L1 Group Limited | Institution | 1.235.514 | 1,17% | US$ 2,16M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 918.857 | 0,87% | US$ 1,61M | 2026-03-31 |
| Point72 Asset Management, L.P. | Institution | 755.842 | 0,72% | US$ 1,32M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 703.323 | 0,67% | US$ 1,23M | 2026-03-31 |
| Nomura Investment Management Business Trust | Institution | 620.000 | 0,59% | US$ 1,09M | 2026-03-31 |
| Walleye Capital LLC | Institution | 607.529 | 0,58% | US$ 1,06M | 2026-03-31 |
| M28 Capital Management LP | Institution | 599.793 | 0,57% | US$ 1,05M | 2026-03-31 |
| Raymond James Financial, Inc. | Institution | 546.079 | 0,52% | US$ 955,64k | 2026-03-31 |
| Monaco Asset Management S.A.M. | Institution | 418.803 | 0,40% | US$ 732,91k | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 355.283 | 0,34% | US$ 621,75k | 2026-03-31 |
| UBS Asset Management AG | Institution | 305.264 | 0,29% | US$ 534,21k | 2026-03-31 |
| Northern Trust Global Investments | Institution | 291.314 | 0,28% | US$ 509,80k | 2026-03-31 |
| Medical Strategy GmbH | Institution | 240.453 | 0,23% | US$ 420,79k | 2025-12-31 |
| Millennium Management LLC | Institution | 194.246 | 0,18% | US$ 339,93k | 2026-03-31 |
| Palo Alto Investors LP | Institution | 188.807 | 0,18% | US$ 330,41k | 2026-03-31 |
| Bank of America Corporation | Institution | 185.110 | 0,18% | US$ 323,94k | 2026-03-31 |
| Diadema Partners LP | Institution | 180.083 | 0,17% | US$ 315,15k | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 172.349 | 0,16% | US$ 301,61k | 2026-03-31 |
| Franklin Street Advisors, Inc. | Institution | 150.000 | 0,14% | US$ 262,50k | 2026-03-31 |
| Marshall Wace LLP | Institution | 115.945 | 0,11% | US$ 202,90k | 2026-03-31 |
| GSA Capital Partners LLP | Institution | 114.256 | 0,11% | US$ 199,95k | 2026-03-31 |
| Deutsche Asset & Wealth Management | Institution | 108.762 | 0,10% | US$ 190,33k | 2026-03-31 |
| Graham Capital Management, L.P. | Institution | 91.553 | 0,09% | US$ 160,22k | 2026-03-31 |
| OneDigital Investment Advisors, LLC | Institution | 85.000 | 0,08% | US$ 148,75k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 84.909 | 0,08% | US$ 148,59k | 2026-03-31 |
| XTX Markets Limited | Institution | 77.287 | 0,07% | US$ 135,25k | 2026-03-31 |
| Lynx1 Capital Management LP | Institution | 68.486 | 0,07% | US$ 119,85k | 2026-03-31 |
| Persistent Asset Partners Limited | Institution | 46.067 | 0,04% | US$ 80,62k | 2026-03-31 |
| Velan Capital Partners LP | Institution | 45.000 | 0,04% | US$ 78,75k | 2026-03-31 |
| Invesco Capital Management LLC | Institution | 44.592 | 0,04% | US$ 78,04k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 33.289 | 0,03% | US$ 58,26k | 2026-03-31 |