| Perceptive Capital Solutions Holdings | Institution | 2.352.500 | 21,26% | US$ 26,42M | 2024-12-31 |
| Farallon Capital Management, L.L.C. | Institution | 2.250.000 | 20,33% | US$ 25,27M | 2026-03-31 |
| One Fin Capital Management LP | Institution | 843.482 | 7,62% | US$ 9,47M | 2026-03-31 |
| RA Capital Management, L.P. | Institution | 750.000 | 6,78% | US$ 8,42M | 2026-03-31 |
| RA Capital Healthcare Fund, L.P. | Institution | 750.000 | 6,78% | US$ 8,42M | 2025-12-05 |
| RTW Investments, LP | Institution | 742.500 | 6,71% | US$ 8,34M | 2026-03-31 |
| BIT Capital GmbH | Institution | 740.264 | 6,69% | US$ 8,31M | 2026-03-31 |
| Holocene Advisors, LP | Institution | 625.173 | 5,65% | US$ 7,02M | 2026-03-31 |
| IPConcept Fund Management SA | Institution | 620.264 | 5,60% | US$ 6,97M | 2025-12-08 |
| One Fin Capital Master Fund Lp | Institution | 603.072 | 5,45% | US$ 6,77M | 2026-01-06 |
| Aberdeen Group Plc | Institution | 578.565 | 5,23% | US$ 6,50M | 2026-04-01 |
| 683 Capital Management, LLC | Institution | 561.923 | 5,08% | US$ 6,31M | 2026-03-31 |
| FMR LLC | Institution | 505.223 | 4,56% | US$ 5,67M | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 499.581 | 4,51% | US$ 5,61M | 2026-03-31 |
| Sculptor Capital Management, Inc. | Institution | 424.700 | 3,84% | US$ 4,77M | 2026-03-31 |
| ADAR1 Partners, LP | Institution | 402.925 | 3,64% | US$ 4,52M | 2025-12-31 |
| Empyrean Capital Partners, LP | Institution | 282.100 | 2,55% | US$ 3,17M | 2026-03-31 |
| Ikarian Capital, LLC | Institution | 240.951 | 2,18% | US$ 2,71M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 162.434 | 1,47% | US$ 1,82M | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 161.437 | 1,46% | US$ 1,81M | 2026-03-31 |
| Alpha Wave Global, LP | Institution | 156.988 | 1,42% | US$ 1,76M | 2026-03-31 |
| Shay Capital LLC | Institution | 150.984 | 1,36% | US$ 1,70M | 2026-03-31 |
| Lighthouse Investment Partners, LLC | Institution | 150.750 | 1,36% | US$ 1,69M | 2026-03-31 |
| DLD Asset Management, LP | Institution | 126.083 | 1,14% | US$ 1,42M | 2026-03-31 |
| LMR Partners LLP | Institution | 117.421 | 1,06% | US$ 1,32M | 2026-03-31 |
| CRCM L.P. | Institution | 116.245 | 1,05% | US$ 1,31M | 2026-03-31 |
| CRCM Institutional Master Fund (BVI), Ltd | Institution | 99.600 | 0,90% | US$ 1,12M | 2026-03-31 |
| Lineage Point Capital LP | Institution | 80.258 | 0,73% | US$ 901,30k | 2026-03-31 |
| FNY Investment Advisers, LLC | Institution | 65.370 | 0,59% | US$ 734,11k | 2026-03-31 |
| Millennium Management LLC | Institution | 62.264 | 0,56% | US$ 699,22k | 2026-03-31 |
| Spearhead Insurance Solutions Idf, Llc | Institution | 53.795 | 0,49% | US$ 604,12k | 2025-12-31 |
| Eagle Health Investments LP | Institution | 37.686 | 0,34% | US$ 423,21k | 2026-03-31 |
| Longaeva Partners L.P. | Institution | 36.614 | 0,33% | US$ 411,18k | 2026-03-31 |
| J. Goldman & Co., L.P. | Institution | 31.428 | 0,28% | US$ 352,94k | 2026-03-31 |
| Mr. Mark McKenna | Insider | 30.000 | 0,27% | US$ 336,90k | 2024-12-31 |
| Dr. Kenneth Song | Insider | 30.000 | 0,27% | US$ 336,90k | 2024-12-31 |
| Dr. Harlan Waksal | Insider | 30.000 | 0,27% | US$ 336,90k | 2024-12-31 |
| Moore Capital Management, LP | Institution | 25.000 | 0,23% | US$ 280,75k | 2026-03-31 |
| Shaolin Capital Management LLC | Institution | 25.000 | 0,23% | US$ 280,75k | 2026-03-31 |
| Virtu Financial, Inc. | Institution | 23.234 | 0,21% | US$ 260,92k | 2026-03-31 |
| Schonfeld Strategic Advisors LLC | Institution | 15.030 | 0,14% | US$ 168,79k | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 13.851 | 0,13% | US$ 155,55k | 2026-03-31 |
| Hudson River Trading LLC | Institution | 11.045 | 0,10% | US$ 124,04k | 2026-03-31 |
| Readystate Asset Management LP | Institution | 10.987 | 0,10% | US$ 123,38k | 2026-03-31 |