| BlackRock, Inc. | Institution | 16.826.695 | 7,17% | US$ 2,99M | 2026-03-31 |
| Kalehua Capital Management LLC | Institution | 10.236.293 | 4,36% | US$ 1,82M | 2026-03-31 |
| AQR Capital Management, LLC | Institution | 10.038.462 | 4,28% | US$ 1,78M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 9.394.593 | 4,00% | US$ 1,67M | 2026-03-31 |
| Arch Venture Partners, L.P. | Institution | 8.055.916 | 3,43% | US$ 1,43M | 2026-03-31 |
| Octagon Capital Advisors LP | Institution | 7.750.000 | 3,30% | US$ 1,38M | 2026-03-31 |
| Samsara BioCapital LLC | Institution | 7.222.559 | 3,08% | US$ 1,28M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 5.922.298 | 2,52% | US$ 1,05M | 2026-03-31 |
| Mr. Faheem Hasnain | Insider | 5.528.366 | 2,36% | US$ 982,94k | 2026-05-12 |
| Acadian Asset Management LLC | Institution | 5.277.904 | 2,25% | US$ 938,41k | 2026-03-31 |
| Artal Group S.A. | Institution | 5.208.968 | 2,22% | US$ 926,15k | 2026-03-31 |
| Invus Public Equities, L.P. | Institution | 5.208.968 | 2,22% | US$ 926,15k | 2024-12-31 |
| 683 Capital Management, LLC | Institution | 5.000.000 | 2,13% | US$ 889,00k | 2026-03-31 |
| 683 Capital Partners, LP | Institution | 5.000.000 | 2,13% | US$ 889,00k | 2026-03-24 |
| Hillhouse Investment Management, Ltd. | Institution | 4.974.041 | 2,12% | US$ 884,38k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 4.939.691 | 2,10% | US$ 878,28k | 2026-03-31 |
| Qube Research & Technologies Ltd | Institution | 4.917.763 | 2,10% | US$ 874,38k | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 4.780.851 | 2,04% | US$ 850,04k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 4.388.109 | 1,87% | US$ 780,21k | 2026-03-31 |
| NEA 18 Venture Growth Equity, L.P. | Institution | 4.065.134 | 1,73% | US$ 722,78k | 2026-02-23 |
| Corient Private Wealth LLC | Institution | 3.985.383 | 1,70% | US$ 708,60k | 2026-03-31 |
| Squarepoint OPS LLC | Institution | 3.398.757 | 1,45% | US$ 604,30k | 2026-03-31 |
| GSA Capital Partners LLP | Institution | 3.254.233 | 1,39% | US$ 578,60k | 2026-03-31 |
| Bank of America Corporation | Institution | 3.173.725 | 1,35% | US$ 564,29k | 2026-03-31 |
| Barclays Bank PLC | Institution | 3.006.112 | 1,28% | US$ 534,49k | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 2.161.079 | 0,92% | US$ 384,24k | 2026-03-31 |
| Alyeska Investment Group, L.P. | Institution | 2.051.442 | 0,87% | US$ 364,75k | 2026-03-31 |
| UBS Asset Management AG | Institution | 1.883.583 | 0,80% | US$ 334,90k | 2026-03-31 |
| Ensign Peak Advisors, Inc. | Institution | 1.702.125 | 0,73% | US$ 302,64k | 2026-03-31 |
| Jacobs Levy Equity Management Inc | Institution | 1.695.159 | 0,72% | US$ 301,40k | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 1.609.492 | 0,69% | US$ 286,17k | 2026-03-31 |
| Mackenzie Financial Corporation | Institution | 1.536.923 | 0,65% | US$ 273,26k | 2026-03-31 |
| MB Generational Wealth, LLC | Institution | 1.532.142 | 0,65% | US$ 272,41k | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 1.510.076 | 0,64% | US$ 268,49k | 2026-03-31 |
| Northern Trust Global Investments | Institution | 1.408.960 | 0,60% | US$ 250,51k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 1.404.285 | 0,60% | US$ 249,68k | 2026-03-31 |
| Deutsche Asset & Wealth Management | Institution | 1.305.886 | 0,56% | US$ 232,19k | 2026-03-31 |
| Octagon Investments Master Fund LP | Institution | 1.226.054 | 0,52% | US$ 217,99k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 1.217.868 | 0,52% | US$ 216,54k | 2026-03-31 |
| New Enterprise Associates, Inc. | Institution | 1.000.000 | 0,43% | US$ 177,80k | 2026-03-31 |