| Suvretta Capital Management, LLC | Institution | 2.020.103 | 7,84% | US$ 56,60M | 2026-06-15 |
| Averill Master Fund, Ltd. | Institution | 1.722.652 | 6,68% | US$ 48,27M | 2026-06-15 |
| Mr. Anand Parikh | Insider | 817.699 | 3,17% | US$ 22,91M | 2026-06-22 |
| Vivo Capital, LLC | Institution | 722.020 | 2,80% | US$ 20,23M | 2026-03-31 |
| Cormorant Asset Management, LP | Institution | 306.222 | 1,19% | US$ 8,58M | 2026-03-31 |
| H&S Ventures LLC | Institution | 222.081 | 0,86% | US$ 6,22M | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 133.506 | 0,52% | US$ 3,74M | 2026-03-31 |
| StemPoint Capital LP | Institution | 132.873 | 0,52% | US$ 3,72M | 2026-03-31 |
| Dr. James Peyer | Insider | 130.142 | 0,50% | US$ 3,65M | 2026-06-01 |
| Cambrian BioPharma, Inc. | Institution | 130.142 | 0,50% | US$ 3,65M | 2026-06-01 |
| Caligan Partners, LP | Institution | 126.002 | 0,49% | US$ 3,53M | 2026-03-31 |
| Trails Edge Biotechnology Master Fund, Lp | Institution | 125.000 | 0,48% | US$ 3,50M | 2026-02-18 |
| Trails Edge Capital Partners, LP | Institution | 125.000 | 0,48% | US$ 3,50M | 2026-03-31 |
| Marshall Wace LLP | Institution | 65.730 | 0,25% | US$ 1,84M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 61.568 | 0,24% | US$ 1,73M | 2026-03-31 |
| Hudson River Trading LLC | Institution | 58.001 | 0,23% | US$ 1,63M | 2026-03-31 |
| Dr. Brian Stephenson | Insider | 46.688 | 0,18% | US$ 1,31M | 2026-07-01 |
| Dr. Stephen Hahn | Insider | 44.763 | 0,17% | US$ 1,25M | 2026-06-15 |
| Millennium Management LLC | Institution | 41.561 | 0,16% | US$ 1,16M | 2026-06-01 |
| Ics Opportunities II Llc | Institution | 41.561 | 0,16% | US$ 1,16M | 2026-06-01 |
| Bank of America Corporation | Institution | 33.025 | 0,13% | US$ 925,36k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 32.041 | 0,12% | US$ 897,79k | 2026-03-31 |
| Logos Global Management, L.P. | Institution | 30.000 | 0,12% | US$ 840,60k | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 26.124 | 0,10% | US$ 731,99k | 2026-03-31 |
| Brevan Howard Capital Management LP | Institution | 20.333 | 0,08% | US$ 569,73k | 2026-03-31 |
| Fred Alger Management, LLC | Institution | 18.337 | 0,07% | US$ 513,80k | 2026-03-31 |
| Mr. Thomas Ricks | Insider | 17.192 | 0,07% | US$ 481,72k | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 16.205 | 0,06% | US$ 454,06k | 2026-03-31 |
| Catalio Capital Management, LP | Institution | 14.718 | 0,06% | US$ 412,40k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 9.501 | 0,04% | US$ 266,22k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 8.872 | 0,03% | US$ 248,59k | 2026-03-31 |
| Morgan Stanley | Institution | 8.785 | 0,03% | US$ 246,16k | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 7.750 | 0,03% | US$ 217,16k | 2026-03-31 |
| Ikarian Capital, LLC | Institution | 6.351 | 0,02% | US$ 177,96k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 6.307 | 0,02% | US$ 176,72k | 2026-03-31 |
| UBS Asset Management AG | Institution | 4.529 | 0,02% | US$ 126,90k | 2026-03-31 |
| Tower Research Capital Europe Limited | Institution | 1.496 | 0,01% | US$ 41,92k | 2026-03-31 |
| Mr. Robert Holmen | Insider | 1.279 | 0,00% | US$ 35,84k | 2026-03-31 |
| Mr. John Celebi | Insider | 1.000 | 0,00% | US$ 28,02k | 2026-03-31 |
| Mr. Christopher Gerry | Insider | 953 | 0,00% | US$ 26,70k | 2026-03-31 |