| Flagship Pioneering, Inc | Institution | 12.674.120 | 21,59% | US$ 47,40M | 2026-03-31 |
| Flagship Ventures Fund V, L.P. | Institution | 9.330.878 | 15,89% | US$ 34,90M | 2026-01-13 |
| FMR LLC | Institution | 6.047.198 | 10,30% | US$ 22,62M | 2026-03-31 |
| BVF Partners L.P. | Institution | 5.842.000 | 9,95% | US$ 21,85M | 2026-03-31 |
| Deerfield Partners, LP | Institution | 5.139.523 | 8,75% | US$ 19,22M | 2026-03-31 |
| Deerfield Management Company, L.P. | Institution | 4.394.367 | 7,48% | US$ 16,43M | 2026-03-31 |
| Eli Lilly and Company | Institution | 4.000.000 | 6,81% | US$ 14,96M | 2026-04-20 |
| Dr. Cigall Kadoch | Insider | 3.624.379 | 6,17% | US$ 13,56M | 2026-04-20 |
| Biotechnology Value Fund L.P. | Institution | 3.139.797 | 5,35% | US$ 11,74M | 2026-03-31 |
| Raymond James Financial, Inc. | Institution | 2.602.382 | 4,43% | US$ 9,73M | 2026-03-31 |
| BlackRock, Inc. | Institution | 2.364.866 | 4,03% | US$ 8,84M | 2026-03-31 |
| Biotechnology Value Fund II, L.P. | Institution | 2.218.382 | 3,78% | US$ 8,30M | 2026-03-31 |
| The Klarman Family Foundation | Institution | 2.139.639 | 3,64% | US$ 8,00M | 2024-09-30 |
| Flagship Pioneering Special Opportunities Fund II, L.P. | Institution | 1.851.801 | 3,15% | US$ 6,93M | 2026-01-13 |
| Euclidean Capital LLC | Institution | 1.573.761 | 2,68% | US$ 5,89M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.495.089 | 2,55% | US$ 5,59M | 2026-03-31 |
| Flagship Ventures Opportunities Fund I, L.P. | Institution | 1.491.441 | 2,54% | US$ 5,58M | 2026-01-13 |
| Geode Capital Management, LLC | Institution | 848.172 | 1,44% | US$ 3,17M | 2026-03-31 |
| Artal Group S.A. | Institution | 720.720 | 1,23% | US$ 2,70M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 679.787 | 1,16% | US$ 2,54M | 2026-03-31 |
| Mr. Adrian H. Gottschalk | Insider | 511.704 | 0,87% | US$ 1,91M | 2026-04-20 |
| Columbia Management Investment Advisers, LLC | Institution | 448.976 | 0,76% | US$ 1,68M | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 406.425 | 0,69% | US$ 1,52M | 2026-03-31 |
| Biotechnology Value Trading Fund OS LP | Institution | 402.467 | 0,69% | US$ 1,51M | 2026-03-31 |
| Candriam, Société En Commandite Par Actions | Institution | 313.765 | 0,53% | US$ 1,17M | 2026-03-31 |
| Jacobs Levy Equity Management Inc | Institution | 303.757 | 0,52% | US$ 1,14M | 2026-03-31 |
| Birchview Capital, LP | Institution | 281.730 | 0,48% | US$ 1,05M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 275.875 | 0,47% | US$ 1,03M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 255.931 | 0,44% | US$ 957,18k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 240.586 | 0,41% | US$ 899,79k | 2026-03-31 |
| Citadel Advisors LLC | Institution | 200.013 | 0,34% | US$ 748,05k | 2026-03-31 |
| Woodline Partners LP | Institution | 180.333 | 0,31% | US$ 674,45k | 2026-03-31 |
| Dr. Steven Bellon | Insider | 151.957 | 0,26% | US$ 568,32k | 2026-04-20 |
| Sio Capital Management, LLC | Institution | 122.889 | 0,21% | US$ 459,60k | 2026-03-31 |
| PanAgora Asset Management, Inc. | Institution | 115.063 | 0,20% | US$ 430,34k | 2026-03-31 |
| Dafna Capital Management, LLC | Institution | 111.859 | 0,19% | US$ 418,35k | 2026-03-31 |
| SCS Capital Management LLC | Institution | 106.980 | 0,18% | US$ 400,11k | 2026-03-31 |