| RA Capital Management, L.P. | Institution | 11.300.939 | 19,74% | US$ 156,18M | 2026-04-29 |
| Pontifax Venture Capital | Institution | 5.206.380 | 9,09% | US$ 71,95M | 2026-03-31 |
| RA Capital Healthcare Fund, L.P. | Institution | 3.403.429 | 5,94% | US$ 47,04M | 2026-04-29 |
| MPM BioImpact LLC | Institution | 2.593.439 | 4,53% | US$ 35,84M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 1.916.968 | 3,35% | US$ 26,49M | 2026-03-31 |
| Braidwell LP | Institution | 1.529.675 | 2,67% | US$ 21,14M | 2026-03-31 |
| Great Point Partners, LLC | Institution | 1.334.130 | 2,33% | US$ 18,44M | 2026-03-31 |
| Millennium Management LLC | Institution | 1.276.260 | 2,23% | US$ 17,64M | 2026-03-31 |
| RA Capital Nexus Fund, L.P. | Institution | 1.226.497 | 2,14% | US$ 16,95M | 2026-04-29 |
| Vanguard Capital Management, LLC | Institution | 1.178.659 | 2,06% | US$ 16,29M | 2026-03-31 |
| Kynam Capital Management, LP | Institution | 1.003.341 | 1,75% | US$ 13,87M | 2026-03-31 |
| Marshall Wace LLP | Institution | 773.123 | 1,35% | US$ 10,68M | 2026-03-31 |
| Affinity Asset Advisors, LLC | Institution | 700.000 | 1,22% | US$ 9,67M | 2026-03-31 |
| Silverarc Capital Management, LLC | Institution | 684.908 | 1,20% | US$ 9,47M | 2026-03-31 |
| Driehaus Capital Management LLC | Institution | 600.946 | 1,05% | US$ 8,31M | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 597.662 | 1,04% | US$ 8,26M | 2026-03-31 |
| RA Capital Nexus Fund II, L.P. | Institution | 483.679 | 0,84% | US$ 6,68M | 2026-04-29 |
| Nan Fung Trinity (HK) Limited | Institution | 420.517 | 0,73% | US$ 5,81M | 2026-03-31 |
| Sphera Funds Management Ltd | Institution | 419.247 | 0,73% | US$ 5,79M | 2026-03-31 |
| BlackRock, Inc. | Institution | 401.649 | 0,70% | US$ 5,55M | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 398.459 | 0,70% | US$ 5,51M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 345.663 | 0,60% | US$ 4,78M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 312.999 | 0,55% | US$ 4,33M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 310.606 | 0,54% | US$ 4,29M | 2026-03-31 |
| Diadema Partners LP | Institution | 286.126 | 0,50% | US$ 3,95M | 2026-03-31 |
| TD Asset Management, Inc. | Institution | 250.102 | 0,44% | US$ 3,46M | 2026-03-31 |
| Morgan Stanley | Institution | 232.131 | 0,41% | US$ 3,21M | 2026-03-31 |
| Longaeva Partners L.P. | Institution | 217.768 | 0,38% | US$ 3,01M | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 217.300 | 0,38% | US$ 3,00M | 2026-03-31 |
| Superstring Capital Management LP | Institution | 199.209 | 0,35% | US$ 2,75M | 2026-03-31 |
| Jane Street Group, LLC | Institution | 171.375 | 0,30% | US$ 2,37M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 158.660 | 0,28% | US$ 2,19M | 2026-03-31 |
| Manulife Asset Management | Institution | 156.317 | 0,27% | US$ 2,16M | 2026-03-31 |
| Verdad Advisers, L.P. | Institution | 144.540 | 0,25% | US$ 2,00M | 2026-03-31 |
| Bridgeway Capital Management, LLC | Institution | 134.300 | 0,23% | US$ 1,86M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 132.000 | 0,23% | US$ 1,82M | 2026-03-31 |
| Seven Fleet Capital Management LP | Institution | 130.654 | 0,23% | US$ 1,81M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 127.904 | 0,22% | US$ 1,77M | 2026-03-31 |
| Botty Investors LLC | Institution | 121.400 | 0,21% | US$ 1,68M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 113.608 | 0,20% | US$ 1,57M | 2026-03-31 |