| AWM Investment Company Inc | Institution | 500.000 | 3,91% | US$ 3,17M | 2025-09-30 |
| Boxer Capital Management, LLC | Institution | 477.515 | 3,74% | US$ 3,03M | 2026-03-31 |
| Symbiosis Capital Partners, LLC | Institution | 431.094 | 3,37% | US$ 2,73M | 2026-03-31 |
| Armistice Capital LLC | Institution | 419.101 | 3,28% | US$ 2,66M | 2024-12-31 |
| Armistice Capital Master Fund Ltd. | Institution | 419.101 | 3,28% | US$ 2,66M | 2024-12-31 |
| Vanguard Capital Management, LLC | Institution | 308.230 | 2,41% | US$ 1,95M | 2026-03-31 |
| Scoggin Capital Management LLC | Institution | 300.000 | 2,35% | US$ 1,90M | 2026-03-31 |
| Vivo Capital, LLC | Institution | 277.778 | 2,17% | US$ 1,76M | 2026-03-31 |
| Special Situations Fund III QP, L.P. | Institution | 269.121 | 2,11% | US$ 1,70M | 2025-09-30 |
| Ensign Peak Advisors, Inc. | Institution | 257.872 | 2,02% | US$ 1,63M | 2026-03-31 |
| Special Situations Life Sciences Fund, L.P | Institution | 150.000 | 1,17% | US$ 950,25k | 2025-09-30 |
| Geode Capital Management, LLC | Institution | 95.874 | 0,75% | US$ 607,36k | 2026-03-31 |
| Special Situations Cayman Fund, L.P. | Institution | 80.879 | 0,63% | US$ 512,37k | 2025-09-30 |
| Lunt Capital Management Inc. | Institution | 52.260 | 0,41% | US$ 331,07k | 2026-03-31 |
| Peak6 Group LLC | Institution | 50.012 | 0,39% | US$ 316,83k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 43.715 | 0,34% | US$ 276,93k | 2026-03-31 |
| Parsons Capital Management, Inc. | Institution | 37.243 | 0,29% | US$ 235,93k | 2026-03-31 |
| BlackRock, Inc. | Institution | 33.799 | 0,26% | US$ 214,12k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 29.801 | 0,23% | US$ 188,79k | 2026-03-31 |
| Vivo Opportunity Cayman Fund,L.P. | Institution | 25.484 | 0,20% | US$ 161,44k | 2026-03-31 |
| Morgan Stanley | Institution | 19.832 | 0,16% | US$ 125,64k | 2026-03-31 |
| Northern Trust Global Investments | Institution | 16.143 | 0,13% | US$ 102,27k | 2026-03-31 |
| Penn Davis McFarland, Inc. | Institution | 11.000 | 0,09% | US$ 69,69k | 2026-03-31 |
| Wells Fargo & Company | Institution | 5.927 | 0,05% | US$ 37,55k | 2026-03-31 |
| Vanguard Global Advisers, LLC | Institution | 5.609 | 0,04% | US$ 35,53k | 2026-03-31 |
| Edward Jones Trust Company | Institution | 5.000 | 0,04% | US$ 31,68k | 2026-03-31 |
| UBS Asset Management AG | Institution | 3.977 | 0,03% | US$ 25,19k | 2026-03-31 |
| The PNC Financial Services Group, Inc. | Institution | 2.735 | 0,02% | US$ 17,33k | 2026-03-31 |
| Atlantic Private Wealth, LLC | Institution | 2.205 | 0,02% | US$ 13,97k | 2026-03-31 |
| Osaic Wealth, Inc. | Institution | 1.926 | 0,02% | US$ 12,20k | 2026-03-31 |
| Group One Trading LLC | Institution | 686 | 0,01% | US$ 4,35k | 2026-03-31 |
| Arax Advisory Partners, LLC | Institution | 570 | 0,00% | US$ 3,61k | 2026-03-31 |
| Tower Research Capital Europe Limited | Institution | 444 | 0,00% | US$ 2,81k | 2026-03-31 |
| MAI Capital Management, LLC | Institution | 100 | 0,00% | US$ 633,50 | 2026-03-31 |
| SBI Holdings, Inc. | Institution | 25 | 0,00% | US$ 158,38 | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 23 | 0,00% | US$ 145,71 | 2026-03-31 |
| U.S. Bancorp Asset Management, Inc. | Institution | 20 | 0,00% | US$ 126,70 | 2026-03-31 |
| Bank of America Corporation | Institution | 0 | 0,00% | - | 2026-03-31 |