| T. Rowe Price Group, Inc. | Institution | 10.563.103 | 18,43% | US$ 21,23M | 2026-03-31 |
| New Enterprise Associates, Inc. | Institution | 4.448.757 | 7,76% | US$ 8,94M | 2026-03-31 |
| New Enterprise Associates 16, L.P. | Institution | 4.448.757 | 7,76% | US$ 8,94M | 2026-03-20 |
| Biotech Growth N.V. | Institution | 2.733.547 | 4,77% | US$ 5,49M | 2025-03-19 |
| Acadian Asset Management LLC | Institution | 2.348.651 | 4,10% | US$ 4,72M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.850.468 | 3,23% | US$ 3,72M | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 1.643.747 | 2,87% | US$ 3,30M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 1.301.664 | 2,27% | US$ 2,62M | 2026-03-31 |
| BlackRock, Inc. | Institution | 1.106.840 | 1,93% | US$ 2,22M | 2026-03-31 |
| Connor, Clark & Lunn Investment Management Ltd. | Institution | 1.058.397 | 1,85% | US$ 2,13M | 2026-03-31 |
| Bridgeway Capital Management, LLC | Institution | 953.654 | 1,66% | US$ 1,92M | 2026-03-31 |
| Mackenzie Financial Corporation | Institution | 844.835 | 1,47% | US$ 1,70M | 2026-03-31 |
| Marshall Wace LLP | Institution | 836.266 | 1,46% | US$ 1,68M | 2026-03-31 |
| Arrowstreet Capital, Limited Partnership | Institution | 834.570 | 1,46% | US$ 1,68M | 2026-03-31 |
| FMR LLC | Institution | 623.779 | 1,09% | US$ 1,25M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 575.882 | 1,01% | US$ 1,16M | 2026-03-31 |
| UBS Asset Management AG | Institution | 565.113 | 0,99% | US$ 1,14M | 2026-03-31 |
| Numeric Investors LLC | Institution | 559.700 | 0,98% | US$ 1,12M | 2026-03-31 |
| Winton Capital Group Limited | Institution | 538.259 | 0,94% | US$ 1,08M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 536.575 | 0,94% | US$ 1,08M | 2026-03-31 |
| AWM Investment Company Inc | Institution | 525.000 | 0,92% | US$ 1,06M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 510.811 | 0,89% | US$ 1,03M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 502.652 | 0,88% | US$ 1,01M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 464.708 | 0,81% | US$ 934,06k | 2026-03-31 |
| D. E. Shaw & Co., L.P. | Institution | 363.921 | 0,64% | US$ 731,48k | 2026-03-31 |
| GlobeFlex Capital LP | Institution | 305.276 | 0,53% | US$ 613,60k | 2026-03-31 |
| Stifel Asset Management Corp. | Institution | 278.645 | 0,49% | US$ 560,08k | 2026-03-31 |
| Round Rock Advisors LLC | Institution | 274.367 | 0,48% | US$ 551,48k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 259.908 | 0,45% | US$ 522,42k | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 252.505 | 0,44% | US$ 507,54k | 2026-03-31 |
| 683 Capital Management, LLC | Institution | 247.958 | 0,43% | US$ 498,40k | 2026-03-31 |