| T. Rowe Price Group, Inc. | Institution | 7.981.978 | 12,15% | US$ 162,91M | 2026-03-31 |
| RA Capital Management, L.P. | Institution | 7.255.993 | 11,04% | US$ 148,09M | 2026-03-31 |
| Biocon Limited | Institution | 5.523.897 | 8,41% | US$ 112,74M | 2026-04-15 |
| Vestal Point Capital, LP | Institution | 5.425.000 | 8,26% | US$ 110,72M | 2026-03-31 |
| Invus Public Equities, L.P. | Institution | 5.216.969 | 7,94% | US$ 106,48M | 2026-04-15 |
| Artal Group S.A. | Institution | 5.216.969 | 7,94% | US$ 106,48M | 2026-04-15 |
| RA Capital Healthcare Fund, L.P. | Institution | 4.603.418 | 7,01% | US$ 93,96M | 2026-02-26 |
| Deep Track Biotechnology Master Fund, Ltd | Institution | 4.062.500 | 6,18% | US$ 82,92M | 2026-03-31 |
| Deep Track Capital, LP | Institution | 4.062.500 | 6,18% | US$ 82,92M | 2026-03-31 |
| Janus Henderson Group plc | Institution | 3.339.218 | 5,08% | US$ 68,15M | 2026-03-31 |
| Red Tree Venture Fund, L.P. | Institution | 3.170.509 | 4,83% | US$ 64,71M | 2026-03-31 |
| Red Tree Venture Capital | Institution | 3.170.509 | 4,83% | US$ 64,71M | 2026-03-31 |
| TPG Capital, L.P. | Institution | 3.010.425 | 4,58% | US$ 61,44M | 2026-03-31 |
| BlackRock, Inc. | Institution | 2.843.535 | 4,33% | US$ 58,04M | 2026-03-31 |
| RA Capital Nexus Fund III, L.P. | Institution | 2.652.575 | 4,04% | US$ 54,14M | 2026-02-26 |
| Omega Fund Management, LLC | Institution | 2.392.150 | 3,64% | US$ 48,82M | 2026-03-31 |
| RP Management, LLC | Institution | 2.388.150 | 3,63% | US$ 48,74M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.774.220 | 2,70% | US$ 36,21M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 1.659.342 | 2,53% | US$ 33,87M | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 1.605.613 | 2,44% | US$ 32,77M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 1.419.388 | 2,16% | US$ 28,97M | 2026-03-31 |
| Jones Hill Capital LP | Institution | 1.260.136 | 1,92% | US$ 25,72M | 2026-03-31 |
| F-Prime Capital Partners Life Sciences Fund Vii Lp | Institution | 1.115.333 | 1,70% | US$ 22,76M | 2024-09-16 |
| FMR LLC | Institution | 1.078.489 | 1,64% | US$ 22,01M | 2026-03-31 |
| Impresa Management LLC | Institution | 1.022.389 | 1,56% | US$ 20,87M | 2026-03-31 |
| Eight Roads Ventures India Healthcare IV, L.P. | Institution | 1.013.853 | 1,54% | US$ 20,69M | 2024-09-16 |
| Deerfield Partners, LP | Institution | 897.587 | 1,37% | US$ 18,32M | 2024-09-17 |
| Deerfield Private Design Fund V, L.P. | Institution | 897.587 | 1,37% | US$ 18,32M | 2024-09-17 |
| Geode Capital Management, LLC | Institution | 830.906 | 1,26% | US$ 16,96M | 2026-03-31 |
| Fidelity International Ltd | Institution | 679.904 | 1,03% | US$ 13,88M | 2026-03-31 |
| OrbiMed Advisors LLC | Institution | 667.300 | 1,02% | US$ 13,62M | 2026-03-31 |
| Acorn Bioventures | Institution | 643.382 | 0,98% | US$ 13,13M | 2026-03-31 |
| Aisling Capital Management LP | Institution | 568.919 | 0,87% | US$ 11,61M | 2026-03-31 |
| Palo Alto Investors LP | Institution | 550.408 | 0,84% | US$ 11,23M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 524.356 | 0,80% | US$ 10,70M | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 489.095 | 0,74% | US$ 9,98M | 2026-03-31 |
| Dr. Kiran Mazumdar-Shaw | Insider | 449.405 | 0,68% | US$ 9,17M | 2026-04-15 |
| Nan Fung Trinity (HK) Limited | Institution | 427.885 | 0,65% | US$ 8,73M | 2026-03-31 |
| Dafna Capital Management, LLC | Institution | 421.733 | 0,64% | US$ 8,61M | 2026-03-31 |