| MAK Capital One, LLC | Institution | 33.621.487 | 12,63% | US$ 54,13M | 2026-03-31 |
| MAK Capital Fund L.P. | Institution | 30.005.343 | 11,27% | US$ 48,31M | 2025-12-31 |
| Syncona Investment Management Limited | Institution | 28.821.053 | 10,83% | US$ 46,40M | 2026-03-31 |
| Blackstone Inc. | Institution | 20.485.611 | 7,70% | US$ 32,98M | 2026-03-31 |
| Blackstone Life Sciences | Institution | 20.485.611 | 7,70% | US$ 32,98M | 2025-09-30 |
| Armistice Capital Master Fund Ltd. | Institution | 17.500.000 | 6,58% | US$ 28,18M | 2025-12-31 |
| Armistice Capital LLC | Institution | 15.800.000 | 5,94% | US$ 25,44M | 2026-03-31 |
| Qatar Holding LLC | Institution | 15.000.000 | 5,64% | US$ 24,15M | 2025-03-01 |
| Tetragon Partners UK LLP | Institution | 9.500.000 | 3,57% | US$ 15,30M | 2026-03-31 |
| Schroder Investment Management Limited | Institution | 9.489.345 | 3,57% | US$ 15,28M | 2026-03-31 |
| Frazier Life Sciences Management, LP | Institution | 4.447.910 | 1,67% | US$ 7,16M | 2026-03-31 |
| AXA Investment Managers S.A. | Institution | 3.361.156 | 1,26% | US$ 5,41M | 2026-03-31 |
| Laurion Capital Management LP | Institution | 3.316.626 | 1,25% | US$ 5,34M | 2026-03-31 |
| Deep Track Biotechnology Master Fund, Ltd | Institution | 2.568.613 | 0,97% | US$ 4,14M | 2025-09-30 |
| Renaissance Technologies LLC | Institution | 2.299.499 | 0,86% | US$ 3,70M | 2026-03-31 |
| Bank of America Corporation | Institution | 1.844.671 | 0,69% | US$ 2,97M | 2026-03-31 |
| BlackRock, Inc. | Institution | 1.480.732 | 0,56% | US$ 2,38M | 2026-03-31 |
| UBS Asset Management AG | Institution | 1.305.779 | 0,49% | US$ 2,10M | 2026-03-31 |
| Healthinvest Partners AB | Institution | 1.169.634 | 0,44% | US$ 1,88M | 2025-12-31 |
| Cetera Investment Advisers LLC | Institution | 1.129.074 | 0,42% | US$ 1,82M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 971.691 | 0,37% | US$ 1,56M | 2026-03-31 |
| Morgan Stanley | Institution | 941.823 | 0,35% | US$ 1,52M | 2026-03-31 |
| JP Morgan Asset Management | Institution | 909.544 | 0,34% | US$ 1,46M | 2026-03-31 |
| GV Management Company, LLC | Institution | 698.262 | 0,26% | US$ 1,12M | 2026-03-31 |
| Marex Group plc | Institution | 542.857 | 0,20% | US$ 874,00k | 2026-03-31 |
| Citadel Advisors LLC | Institution | 459.404 | 0,17% | US$ 739,64k | 2026-03-31 |
| Hennion & Walsh Asset Management, Inc. | Institution | 440.206 | 0,17% | US$ 708,73k | 2026-03-31 |
| Point72 Asset Management, L.P. | Institution | 426.983 | 0,16% | US$ 687,44k | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 414.030 | 0,16% | US$ 666,59k | 2026-03-31 |
| Privium Fund Management BV | Institution | 363.430 | 0,14% | US$ 585,12k | 2026-03-31 |
| Edentree Asset Management Limited | Institution | 300.000 | 0,11% | US$ 483,00k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 245.785 | 0,09% | US$ 395,71k | 2026-03-31 |
| Wells Fargo & Company | Institution | 207.856 | 0,08% | US$ 334,65k | 2026-03-31 |
| Millennium Management LLC | Institution | 204.728 | 0,08% | US$ 329,61k | 2026-03-31 |
| Erste Asset Management GmbH | Institution | 195.000 | 0,07% | US$ 313,95k | 2026-03-31 |
| Ashburton (Jersey) Limited | Institution | 192.643 | 0,07% | US$ 310,16k | 2025-09-30 |
| Dafna Capital Management, LLC | Institution | 179.316 | 0,07% | US$ 288,70k | 2026-03-31 |
| Diametric Capital, LP | Institution | 178.731 | 0,07% | US$ 287,76k | 2026-03-31 |