| Takeda Pharmaceutical Company Limited | Institution | 24.307.322 | 6,60% | US$ 414,44M | 2025-12-31 |
| SDIC Innovation Investment Management Co., Ltd. | Institution | 15.696.340 | 4,26% | US$ 267,62M | 2024-09-25 |
| SDIC Advanced Manufacturing Industry Investment Fund (Limtied Partnership) | Institution | 15.696.340 | 4,26% | US$ 267,62M | 2024-09-25 |
| Vanguard Capital Management, LLC | Institution | 8.834.828 | 2,40% | US$ 150,63M | 2026-05-31 |
| Morgan Stanley | Institution | 6.344.903 | 1,72% | US$ 108,18M | 2025-01-30 |
| JPMorgan Chase & Co. | Institution | 6.205.144 | 1,69% | US$ 105,80M | 2025-02-07 |
| BlackRock, Inc. | Institution | 5.350.200 | 1,45% | US$ 91,22M | 2026-05-31 |
| Norges Bank Investment Management | Institution | 4.459.482 | 1,21% | US$ 76,03M | 2025-12-31 |
| Yinhua Fund Management Co., Ltd. | Institution | 3.949.900 | 1,07% | US$ 67,35M | 2025-12-31 |
| China Universal Asset Management Company Ltd. | Institution | 3.009.800 | 0,82% | US$ 51,32M | 2025-06-30 |
| Vanguard Fiduciary Trust Company | Institution | 2.278.772 | 0,62% | US$ 38,85M | 2026-05-31 |
| Bosera Asset Management Co., Ltd. | Institution | 1.875.400 | 0,51% | US$ 31,98M | 2025-06-30 |
| China Asset Management Co. Ltd. | Institution | 1.799.530 | 0,49% | US$ 30,68M | 2026-05-29 |
| Maxwealth Fund Management Co., Ltd | Institution | 1.765.000 | 0,48% | US$ 30,09M | 2025-06-30 |
| E Fund Management Co., Ltd. | Institution | 1.021.420 | 0,28% | US$ 17,42M | 2025-06-30 |
| GF Fund Management Co., Ltd. | Institution | 927.900 | 0,25% | US$ 15,82M | 2025-12-31 |
| Fullgoal Fund Management Co. Ltd. | Institution | 861.900 | 0,23% | US$ 14,70M | 2025-06-30 |
| Harvest Fund Management Co. Ltd. | Institution | 576.200 | 0,16% | US$ 9,82M | 2025-12-31 |
| State Street Global Advisors, Inc. | Institution | 488.100 | 0,13% | US$ 8,32M | 2026-05-31 |
| China Southern Asset Management Co., Ltd. | Institution | 355.300 | 0,10% | US$ 6,06M | 2025-06-30 |
| First Seafront Fund Management Co., Ltd | Institution | 295.000 | 0,08% | US$ 5,03M | 2025-06-30 |
| Penghua Fund Management Co., Ltd. | Institution | 260.800 | 0,07% | US$ 4,45M | 2025-06-30 |
| Teachers Insurance and Annuity Association-College Retirement Equities Fund | Institution | 210.100 | 0,06% | US$ 3,58M | 2026-03-31 |