RNS Number:1616G
Medisys PLC
08 December 2004


                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Name of company

Medisys PLC
...............................................................

2. Name of shareholder having a major interest

Elan Corporation, PLC
...............................................................

3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18

Elan Corporation, PLC
...............................................................

4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them

Elan International Services Limited
...............................................................

5. Number of shares / amount of stock acquired

17,000,000
...............................................................

6. Percentage of issued class

3.6%
...............................................................

7. Number of shares / amount of stock disposed

...............................................................

8. Percentage of issued class

...............................................................

9. Class of security

Ordinary Shares of 1p each
...............................................................

10. Date of transaction

6th December 2004
...............................................................

11. Date company informed

7th December 2004
...............................................................

12. Total holding following this notification

17,000,000
...............................................................

13. Total percentage holding of issued class following this notification

3.6%
...............................................................

14. Any additional information

...............................................................

15. Name of contact and telephone number for queries

Jonathan Chapman (Company Secretary); 020 7563 5200
...............................................................

16. Name and signature of authorised company official responsible for making
this notification

...............................................................

Date of notification

8 December 2004
...............................................................

The FSA does not give any express or implied warranty as to the accuracy of this
document or material and does not accept any liability for error or omission.
The FSA is not liable for any damages (including, without limitation, damages
for loss of business or loss of profits) arising in contract, tort or otherwise
from the use of or inability to use this document, or any material contained in
it, or from any action or decision taken as a result of using this document or
any such material.




                      This information is provided by RNS
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