PBE Invesco Biotechnology and Genome ETF

PowerShares Exchange-Traded Fund Trust

301 West Roosevelt Road

Wheaton, Illinois 60187

August 15, 2008

Mr. James O’Connor

Securities and Exchange Commission

Division of Investment Management

100 F Street, NE

Washington, D.C. 20549

Re:           PowerShares Exchange-Traded Fund Trust—Request for Withdrawal of Post-Effective Amendment Nos. 115, 118, 121, 124, 127, 130, 133, 136, 140, 144, 147, 150, 155, 161, 166, 171, 177, 186, 190  and 200 to the Trust’s Registration Statement filed on Form N-1A under the Securities Act of 1933 (File Nos. 333-102228 and 811-21265 )

Dear Mr. O’Connor:

Pursuant to Rule 477 under the Securities Act of 1933, as amended (the “Act”), PowerShares Exchange-Traded Fund Trust (the “Trust” or the “Registrant”) hereby requests withdrawal of the following Post-Effective Amendments (the “Amendments”), relating to the PowerShares REIT Preferred Portfolio and the PowerShares Value Line 400 Portfolio (the “Funds”) to the Trust’s Registration Statement filed on Form N-1A (File Nos. 333-102228 and 811-21265).

The Registrant is making this application for withdrawal of the Amendments because it has determined not to proceed with the registration of the Funds .  No securities have been issued or sold in connection with the Amendments.

If you have any questions, please feel free to contact Clifford R. Cone at (212) 878-3180. Thank you.

Very truly yours,

PowerShares Exchange-Traded Fund Trust