RNS No 6972a
THERAPEUTIC ANTIBODIES INC


                    DEALINGS BY SUBSTANTIAL SHAREHOLDERS

1)  NAME OF COMPANY

THERAPEUTIC ANTIBODIES INC

2)  NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

HSBC INVESTMENT BANK PLC

PREVIOUSLY INTERESTED IN 4,005,535 SHARES AND NOTIFIED THE COMPANY THAT IT NO
LONGER HAS A NOTIFIABLE INTEREST

3)  Please state whether notification indicates that it is in respect of holding
    of the Shareholder named in 2 above or in respect of a non-beneficial
    interest or in the case of an individual holder if it is a holding of that
    person's spouse or children under the age of 18

SHAREHOLDER NAMED IN 2 ABOVE AND BY VIRTUE OF SECTION 203 OF THE 
COMPANIES ACT 1985 HSBC INVESTMENT BANK HOLDINGS PLC AND HSBC HOLDINGS PLC

4)  Name of the registered holder(s) and, if more than one holder, the number of
    shares held by each of them.

HSBC INVESTMENT BANK PLC

5)  Number of shares/amount of stock acquired.

N/A

6)  ( N/A %) of issued Class

7)  Number of shares/amount of stock disposed

N/A

8)  ( N/A %) of issued Class

9)  Class of security

SHARES OF COMMON STOCK OF US$0.001

10) Date of transaction

16/12/98

11) Date company informed

30/12/98

12) Total holding following this notification

N/A

13) Total percentage holding of issued class following this notification

N/A

14) Any additional information

PREVIOUSLY INTERESTED IN 4,005,535 SHARES AND NOTIFIED THE COMPANY THAT IT NO
LONGER HAS A NOTIFIABLE INTEREST

15) Name of contact and telephone number for queries

PHIL WALKER, WESTLB PANMURE LIMITED
0171  638 4010

16) Name and signature of authorised company official responsible for making
    this notification

    Date of Notification....4/1/99...


END

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