By Val Brickates Kennedy

Drug stocks slid into the red early Monday as shares of Biogen Idec fell on news that another case of brain disease PML had been discovered in a user of its multiple-sclerosis drug Tysabri.

The NYSE Arca Pharmaceutical Index (DRG) slipped 0.5% to 260.05, and the NYSE Arca Biotechnology Index (BTK) dipped 1% to 694.02.

Shares of Biogen (BIIB) were off 6% to $46.99.

On Friday, Biogen reported its tenth case of PML since Tysabri was put back on the market in 2006. It is also the fourth such case reported since mid-May. One person has died of the disorder since the relaunch.

In 2005, the drug was taken off the market for several months after it was linked to PML, a potentially fatal brain disease, in a handful of Tysabri users.

Tysabri is co-marketed with Elan Corp. (ELN). Shares of Elan were down 4% to $7.09.

Shares of Sanofi-Aventis (SNY) rose 3% to $28.76 after falling about 6% Friday.

On Monday, Sanofi once again defended the safety of its long-acting insulin product Lantus, asserting that clinical trials have not associated the product with cancer. The European medical journal Diabetologia over the weekend reportedly questioned whether there might be a link, and called for more medical research into the matter.

Shares of Novo Nordisk A/S (NVO) added 1% to $53.33. Novo Nordisk, which markets a similar product, said Sunday that none of its long-acting insulin products has ever been linked to cancer.

-By Val Brickates Kennedy, 415-439-6400; AskNewswires@dowjones.com