Panitumumab Significantly Improves Progression-Free Survival in Phase 3 Randomized Metastatic Colorectal Cancer Study
03 November 2005 - 2:02PM
PR Newswire (US)
First EGFr Inhibitor to Demonstrate Improvement in Progression-Free
Survival as Monotherapy for Metastatic Colorectal Cancer THOUSAND
OAKS, Calif. and FREMONT, Calif., Nov. 3 /PRNewswire-FirstCall/ --
- Amgen (NASDAQ:AMGN) and Abgenix, Inc. (NASDAQ:ABGX) today
announced that a pivotal Phase 3 study of panitumumab met the
primary endpoint of improving progression-free survival in patients
with metastatic colorectal cancer (mCRC) who had failed standard
chemotherapy. In this randomized Phase 3 trial involving 463
patients, those who received panitumumab every two weeks showed a
46 percent decrease in tumor progression rate versus those who
received best supportive care alone (p
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