OSK Osisko Mining Inc

Osisko Mining Inc. (OSK:TSX. "Osisko" or the "Corporation") is pleased to provide new analytical results from the ongoing drill program at its 100% owned Windfall gold project located in the Abitibi greenstone belt, Urban Township, Eeyou Istchee James Bay, Québec.

Significant new analytical results presented below include 27 intercepts in 8 drill holes (1 from surface, 8 from underground) and 8 wedges. Infill intercepts are located inside defined January 2022 mineral resource estimate (“MRE”) blocks (see Osisko news release dated January 10, 2022). Expansion intercepts are located outside the January 2022 MRE blocks and either expand resource wireframes or are in a defined zone or corridor but do not yet correlate to a specific wireframe.

Osisko Chief Executive Officer John Burzynski commented: “The infill program at Windfall continues to intercept high-grade mineralization. Today’s wide headline hole comes from Triple Lynx wireframe 3161 which has another wide zone of 41.4 g/t Au over 9.0 metres. Infill at Underdog is also returning intercepts of over one ounce per tonne over more than two meters.”

Selected high-grade intercepts include: 58.9 g/t Au over 14.7 metres in WST-21-0996A; 41.4 g/t Au over 9.0 metres in WST-21-0928; 88.0 g/t Au over 3.0 metres in WST-21-0997; 49.8 g/t Au over 3.9 metres in WST-21-0914; 81.5 g/t Au over 2.0 metres in WST-21-0936A; and 60.0 g/t Au over 2.4 metres in OSK-W-21-2463-W3. Maps showing hole locations and full analytical results are available at www.osiskomining.com. Maps: Long Section_In EN 20220329, PR_EN_20220329_Surface, PR_EN_20220329_UG.

Infill Drilling

Hole No.	From (m)	To (m)	Interval (m)	Au (g/t) uncut	Au (g/t) cut to 100 g/t	Zone	Corridor
OSK-W-21-1871-W3	816.3	820.7	4.4	22.6		UDD_4101	Underdog
including	816.3	817.0	0.7	86.0
and	820.2	820.7	0.5	60.6
OSK-W-21-2463-W3	971.5	973.9	2.4	60.0	47.1	UDD_4122	Underdog
including	972.8	973.9	1.1	128	100
OSK-W-21-2544-W1	791.7	794.0	2.3	4.13		TLX_3184	Triple Lynx
including	791.7	792.0	0.3	11.6
	797.7	800.0	2.3	12.2		TLX_3159	Lynx HW
including	798.3	798.9	0.6	45.3
OSK-W-21-2599	702.8	705.8	3.0	4.83		CA2_2208	Caribou
including	702.8	703.5	0.7	16.6
WST-21-0914	250.1	254.0	3.9	49.8	46.3	LSW_3500	Lynx SW
including	250.1	250.4	0.3	146	100
WST-21-0928	273.1	282.1	9.0	41.4	33.0	TLX_3161	Triple Lynx
including	275.8	277.1	1.3	155	96.5
WST-21-0936A	527.0	529.0	2.0	81.5	25.2	LX4_3450	Lynx 4
including	527.8	528.3	0.5	325	100
WST-21-0996A	146.3	161.0	14.7	58.9	32.2	TLX_3161	Triple Lynx
including	150.6	151.3	0.7	650	100
WST-21-0997	589.0	592.0	3.0	88.0	43.0	LX4_3430	Lynx 4
including	589.7	590.7	1.0	235	100
WST-22-1000	166.0	168.1	2.1	5.82		TLX_3163	Triple Lynx
including	167.2	167.7	0.5	22.1
	232.8	235.0	2.2	5.09		TLX_3169	Triple Lynx
	256.4	258.6	2.2	4.43		TLX_3175	Triple Lynx
including	256.4	256.9	0.5	18.1
	372.3	374.5	2.2	4.03		TLX_3191	Triple Lynx
including	373.7	374.5	0.8	9.19
WST-22-1001	503.4	506.3	2.9	6.60		LX4_3404	Lynx 4
including	505.5	505.8	0.3	19.5
WST-22-1006	186.8	189.0	2.2	35.6	14.8	TLX_3121	Triple Lynx
including	186.8	187.1	0.3	252	100
	512.0	518.3	6.3	9.22		LX4_3404	Lynx 4
including	512.3	513.5	1.2	25.7
and	517.8	518.3	0.5	39.4

Notes: True widths are estimated at 55 – 80% of the reported core length interval. See "Quality Control and Reporting Protocols" below. CA2= Caribou 2, LX4 = Lynx 4, LSW = Lynx Southwest, TLX = Triple Lynx and UDD=Underdog.

Expansion Drilling

Hole No.	From (m)	To (m)	Interval (m)	Au (g/t) uncut	Au (g/t) cut to 100 g/t	Zone	Corridor
OSK-W-21-2540-W3	1280.0	1282.0	2.0	17.7		LX4	Lynx 4
including	1281.4	1282.0	0.6	58.6
OSK-W-21-2540-W9	1192.0	1194.0	2.0	3.68		LX4	Lynx 4
	1202.0	1208.0	6.0	7.68		LX4	Lynx 4
including	1207.0	1208.0	1.0	32.9
	1230.0	1232.0	2.0	15.3		LX4	Lynx 4
	1282.7	1287.8	5.1	4.94		LX4	Lynx 4
including	1287.0	1287.8	0.8	19.3
OSK-W-21-2646-W1	1067.0	1070.0	3.0	3.95		TLX	Triple Lynx
OSK-W-22-2540-W12	867.4	869.5	2.1	6.29		LNX	Lynx
including	868.4	868.7	0.3	39.5
OSK-W-22-2540-W13	879.5	881.8	2.3	7.40		LNX	Lynx
including	879.5	880.4	0.9	18.8
	940.0	942.0	2.0	6.01		TLX	Triple Lynx
including	940.0	940.5	0.5	23.3
WST-22-1006	609.0	611.1	2.1	8.40		LX4	Lynx 4
including	609.9	610.6	0.7	24.8

Notes: True widths are estimated at 55 – 80% of the reported core length interval. See "Quality Control and Reporting Protocols" below., LNX = Lynx, LX4 = Lynx 4 and TLX = Triple Lynx.

Drill hole location

Hole Number	Azimuth (°)	Dip (°)	Length (m)	UTM E	UTM N	Elevation	Section
OSK-W-21-1871-W3	331	-56	906	452496	5434397	402	2475
OSK-W-21-2463-W3	339	-65	1299	452617	5434447	402	2600
OSK-W-21-2540-W3	117	-60	1470	453465	5435640	410	3925
OSK-W-21-2540-W9	117	-60	1349	453465	5435640	410	3925
OSK-W-21-2544-W1	128	-50	1140	452960	5435539	419	3425
OSK-W-21-2599	328	-62	774	452787	5434526	397	2800
OSK-W-21-2646-W1	109	-58	1236	453326	5435648	413	3800
OSK-W-22-2540-W12	117	-60	885	453465	5435640	410	3925
OSK-W-22-2540-W13	117	-60	911	453465	5435640	410	3925
WST-21-0914	148	-59	502	453105	5435066	231	3325
WST-21-0928	154	-70	391	453507	5435327	-7	3800
WST-21-0936A	137	-48	570	453257	5435209	96	3525
WST-21-0996A	143	-45	427	453358	5435297	-149	3675
WST-21-0997	119	-45	640	453506	5435326	-90	3800
WST-22-1000	139	-45	447	453359	5435297	-149	3675
WST-22-1001	124	-46	637	453506	5435326	-90	3800
WST-22-1006	122	-45	610	453506	5435326	-90	3800

Caribou ZoneMineralization most commonly occurs in gold-bearing pyrite stockworks as well as semi-massive pyrite replacement zones associated with phyllic alteration (sericite-pyrite ± silica) with sulphides, pyrite dominated with minor chalcopyrite and sphalerite ranging from trace to up to 20%, and local visible gold. Mineralization is hosted in rhyolites or mafic-intermediate volcanics frequently at or near faults or the contact with felsic porphyritic intrusions.

Lynx ZoneMineralization occurs as grey to translucent quartz-carbonate-pyrite-tourmaline veins and pyrite replacement zones and stockworks. Vein-type mineralization is associated with haloes of pervasive sericite-pyrite ± silica alteration and contain sulphides (predominantly pyrite with minor amounts of chalcopyrite, sphalerite, galena, arsenopyrite, and pyrrhotite) and local visible gold. Replacement mineralization is associated with strong pervasive silica-sericite-ankerite ± tourmaline alteration and contains disseminated pyrite from trace to 80% with local visible gold. Pyrite stockworks can form envelopes that reach several tens of metres in thickness. Fuchsite alteration is common and is spatially constrained to near the gabbros. Mineralization occurs at or near geological contacts between felsic porphyritic or fragmental intrusions and the host rhyolites or gabbros and locally can be hosted along the gabbro-rhyolite contact.

UnderdogMineralization most commonly occurs in gold-bearing quartz-pyrite (± tourmaline) veins and as disseminated, stringer, semi-massive to massive pyrite with minor sphalerite, chalcopyrite and molybdenite associated with strong sericite and silica alteration. Mineralization is hosted along the intrusive contacts of a three-phase composite felsic porphyritic unit which cross-cuts felsic and mafic volcanic sequences.

Qualified PersonThe scientific and technical content of this news release has been reviewed, prepared and approved by Mr. Louis Grenier, M.Sc.A., P.Geo. (OGQ 800), Director of Exploration for Osisko's Windfall gold project, who is a "qualified person" as defined by National Instrument 43-101 – Standards of Disclosure for Mineral Projects ("NI 43-101").

Quality Control and Reporting ProtocolsTrue width determination is estimated at 55-80% of the reported core length interval for the zone. Assays are uncut except where indicated. Intercepts occur within geological confines of major zones but have not been correlated to individual vein domains at this time. Reported intervals include minimum weighted averages of 3.5 g/t Au diluted over core lengths of at least 2.0 metres. NQ core assays were obtained by either 1-kilogram screen fire assay or standard 50-gram fire-assaying-AA finish or gravimetric finish at (i) ALS Laboratories in Val d'Or, Québec, Vancouver, British Colombia, Lima, Peru or Vientiane, Laos (ii) Bureau Veritas in Timmins, Ontario. The 1-kilogram screen assay method is selected by the geologist when samples contain coarse gold or present a higher percentage of pyrite than surrounding intervals. Selected samples are also analyzed for multi-elements, including silver, using a Four Acid Digestion-ICP-MS method at ALS Laboratories. Drill program design, Quality Assurance/Quality Control ("QA/QC") and interpretation of results is performed by qualified persons employing a QA/QC program consistent with NI 43-101 and industry best practices. Standards and blanks are included with every 20 samples for QA/QC purposes by the Corporation as well as the lab. Approximately 5% of sample pulps are sent to secondary laboratories for check assay.

About the Windfall Gold DepositThe Windfall gold deposit is located between Val-d'Or and Chibougamau in the Abitibi region of Québec, Canada. The Mineral Resource Estimate (“MRE“) defined by Osisko, as disclosed in the news release dated January 10, 2022 is supported by the technical report entitled “Mineral Resource Estimate Update for the Windfall Project” dated February 10, 2022 (with an effective date  of October 21, 2021), and assuming a cut-off grade of 3.50 g/t Au, comprises 565,000 tonnes at 11.6 g/t Au (210,000 ounces) in the measured mineral resource category, 8,907,000 tonnes at 10.5 g/t Au (2,994,000 ounces) in the indicated mineral resource category and 13,035,000 tonnes at 8.6 g/t Au (3,585,000 ounces) in the inferred mineral resource category. The key assumptions, parameters and methods used to estimate the mineral resource estimate disclosed in the January 10, 2022, news release, certain of which are described in the January 10, 2022, news release, are further described in the full technical report for this updated mineral resource estimate in accordance with NI 43-101 and is available on SEDAR (www.sedar.com) under the Corporation's issuer profile. The Windfall gold deposit is currently one of the highest-grade resource-stage gold projects in Canada and has world-class scale. Mineralization occurs in three principal zones: Lynx, Main Zone, and Underdog. Mineralization is generally comprised of sub-vertical zones following intrusive porphyry contacts plunging to the northeast. The resources are defined from surface to a depth of 1,600 metres as it now includes the Triple 8 (T8) zone. The resources excluding T8 are defined from surface to a depth of 1,200 metres. The deposit remains open along strike and at depth. Mineralization has been identified at surface in some areas and as deep as 2,625 metres in others with significant potential to extend mineralization down-plunge and at depth.

About Osisko Mining Inc.Osisko is a mineral exploration company focused on the acquisition, exploration, and development of gold resource properties in Canada. Osisko holds a 100% interest in the high-grade Windfall gold deposit located between Val-d'Or and Chibougamau in Québec and holds a 100% undivided interest in a large area of claims in the surrounding Urban Barry area and nearby Quévillon area (over 2,500 square kilometres).

Cautionary Note Regarding Forward-Looking InformationThis news release contains "forward-looking information" within the meaning of the applicable Canadian securities legislation that is based on expectations, estimates, projections and interpretations as at the date of this news release. Any statement that involves predictions, expectations, interpretations, beliefs, plans, projections, objectives, assumptions, future events or performance (often, but not always, using phrases such as "expects", or "does not expect", "is expected", "interpreted", "management's view", "anticipates" or "does not anticipate", "plans", "budget", "scheduled", "forecasts", "estimates", "potential", "feasibility", "believes" or "intends" or variations of such words and phrases or stating that certain actions, events or results "may" or "could", "would", "might" or "will" be taken to occur or be achieved) are not statements of historical fact and may be forward-looking information and are intended to identify forward-looking information. This news release contains the forward-looking information pertaining to, among other things: the Windfall gold deposit being one of the highest-grade resource-stage gold projects in Canada and having world-class scale; the key assumptions, parameters and methods used to estimate the mineral resource estimate disclosed in this news release; the prospects, if any, of the Windfall gold deposit; timing and ability of Osisko to file a technical report for the mineral resource estimate disclosed in this news release; the timing and ability of Osisko, if at all, to publish a feasibility study for the Windfall gold deposit; the amount and type of drilling to be completed and the timing to complete such drilling; the focus of the remaining infill drilling; the trend of grade increase; the Lynx zone remaining open to expansion down plunge; upgrading a inferred mineral resource to a measured mineral resource or indicated mineral resource category; future drilling at the Windfall gold deposit; the significance of historic exploration activities and results. Such factors include, among others, risks relating to the ability of exploration activities (including drill results) to accurately predict mineralization; errors in management's geological modelling; the ability of Osisko to complete further exploration activities, including (infill) drilling; property and royalty interests in the Windfall gold deposit; the ability of the Corporation to obtain required approvals; the results of exploration activities; risks relating to mining activities; the global economic climate; metal prices; dilution; environmental risks; and community and non-governmental actions. Although the forward-looking information contained in this news release is based upon what management believes, or believed at the time, to be reasonable assumptions, Osisko cannot assure shareholders and prospective purchasers of securities of the Corporation that actual results will be consistent with such forward-looking information, as there may be other factors that cause results not to be as anticipated, estimated or intended, and neither Osisko nor any other person assumes responsibility for the accuracy and completeness of any such forward-looking information. Osisko does not undertake, and assumes no obligation, to update or revise any such forward-looking statements or forward-looking information contained herein to reflect new events or circumstances, except as may be required by law.

CONTACT INFORMATION:John BurzynskiChief Executive OfficerTelephone (416) 363-8653