In-depth analysis of obesity highlights latest
advances in weight loss drugs, the search for biological fitness
mediators and the pros and cons of weight as a proxy for
LONDON, Feb. 6, 2023 /PRNewswire/
-- BioWorld™ published by Clarivate
Plc (NYSE:CLVT), a global leader in connecting people and
organizations to intelligence they can trust to transform their
world, explores how difficult scientific detachment can be for
health topics that have large cultural components- such as obesity.
After many years of research and development, drug-induced weight
loss has matured into a viable therapeutic option. Special
investigation from BioWorld provides in-depth analysis of the
latest advances in metabolic health, how fitness may play a role in
these shifts and how scientists' perceptions of the obesity
epidemic may shift.
According to the World Obesity Federation, one billion people
globally will be living with obesity by 2030. With medical
researchers' laser focus on finding solutions to address the
obesity epidemic, excitement is finally building around the next
generation of drugs developed to help adults shed excess weight.
These new classes of drugs offer promising results and may provide
an alternative solution to weight loss other than invasive
procedures such as bariatric surgery. While new weight loss drugs
are an extraordinary advance in medicine and will likely become
some of the most prescribed of all medications in the upcoming
years, how will perceptions in the medical community around the
role of fitness in weight loss and overall health evolve?
Following deep analysis of the latest studies on weight loss,
metabolic health and fitness, BioWorld Science Managing Editor,
Anette Breindl, discusses:
- How difficult scientific detachment can be for health topics
that have large cultural components. Heated debates continue around
the discrepancies between individuals with Body Mass Index (BMI) in
the "overweight" range, often associated with the greatest
longevity, and individuals in the so-called "Class I obesity"
category, who often live as long as those with a "normal" BMI.
- How weight loss is blind to the behavioral differences between
brown and white fats. Weight may be a poor proxy for health as fat
cells are distributed throughout the body, and the details of where
they are and what they are doing matter a great deal.
- The effects of GLP-1R agonists, also called incretin mimetics,
which go far beyond weight loss, and the question of whether weight
loss is causal to their effects.
- How new methods are enabling a molecular understanding of
exercise, which may be much more important to health than weight
Lynn Yoffee, Publisher,
BioWorld said: "Drug-induced weight loss has finally
matured into a viable therapeutic option for patients. At the same
time, there are longstanding concerns that the health effects of
weight might be overrated. Can a person still be considered fit and
healthy despite being over what is considered a normal weight?
BioWorld Science Managing Editor Anette
Breindl has reviewed the latest research around these
challenges and raised several complicated red flags, just as
millions of people are desperately hoping that the new weight loss
pills are the answer in the quest to be healthy."
For more exclusive in-depth coverage of obesity and metabolic
health on BioWorld, visit:
Listen to the latest edition of the BioWorld Insider
podcast, where BioWorld Science Managing Editor Anette Breindl, discusses her new analysis of
multiple studies related to weight loss, metabolic health and
fitness, which in many ways goes against the mainstream health care
state of mind about obesity, here:
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