BBVA BBVA Bilbao Vizcaya Argentaria SA

Banco Bilbao Vizcaya Argentaria, S.A.

Calle Azul 4

28050 Madrid

Spain

March 4, 2022

United States Securities and Exchange Commission

100 F Street, N.E.

Washington, DC 20549

Ladies and Gentlemen:

Pursuant to Section 219 of the Iran Threat Reduction and Syria Human Rights Act of 2012 and Section 13(r) of the Securities Exchange Act of 1934, as amended, notice is hereby provided that Banco Bilbao Vizcaya Argentaria, S.A. has made disclosure pursuant to such provisions in its Annual Report on Form 20-F for the fiscal year ended December 31, 2021, which was filed with the U.S. Securities and Exchange Commission on March 4, 2022. This disclosure can be found on page 55 of such Annual Report on Form 20-F and is incorporated by reference herein.

Respectfully submitted,