ALACT

Regulatory News:

ACTICOR BIOTECH (ISIN: FR0014005OJ5 – ALACT) (Paris:ALACT), a clinical stage biopharmaceutical company dedicated to the development of innovative treatments for cardiovascular emergencies, including ischemic stroke, today announces its half-year report on the liquidity contract with the brokerage firm Kepler Cheuvreux.

Under the liquidity contract entered into between ACTICOR BIOTECH and Kepler Cheuvreux, the following resources appeared on the liquidity account on December 31st 2022:

- 33,819 shares

- € 412,635.83

- Number of executions on buy side on semester: 356

- Number of executions on sell side on semester: 414

- Traded volume on buy side on semester: 31,336 shares for € 191,946.13

- Traded volume on sell side on semester: 41,970 shares for € 283,671.24

As a reminder :

• the following resources appeared on the last half year statement on 30 June 2022 on the liquidity account:

- 44,453 shares

- € 320,248.35

- Number of executions on buy side on semester: 474

- Number of executions on sell side on semester: 454

- Traded volume on buy side on semester: 46,043 shares for € 311,966.95

- Traded volume on sell side on semester: 63,621 shares for € 440,978.86

• the following resources appeared on the liquidity account when the activity started:

- 0 shares

- € 600,000.00

The implementation of this report is carried out in accordance with AMF Decision N°2021-01 of June 22nd 2021 renewing the implementation of liquidity contracts for shares as an accepted market practice.

About ACTICOR BIOTECH

Acticor Biotech is a clinical stage biopharmaceutical company, a spin-off from INSERM (the French National Institute of Health and Medical Research), which is aiming to develop an innovative treatment for cardiovascular emergencies, including ischemic stroke.

Acticor Biotech is developing glenzocimab (ACT017), a humanized monoclonal antibody (mAb) fragment directed against a novel target of major interest, platelet glycoprotein VI (GPVI). Glenzocimab inhibits platelet binding to the thrombus without affecting physiological hemostasis, thereby limiting the bleeding risk, particularly in the brain.

In May 2022, Acticor Biotech presented positive results from its Phase 1b/2a study, ACTIMIS, at the ESOC, confirming the safety profile and showing a reduction in mortality and intracerebral hemorrhage in the glenzocimab-treated group in patients with stroke. The efficacy of glenzocimab is now being evaluated in an international Phase 2/3 study, ACTISAVE, which will include 1,000 patients. In July 2022, Acticor Biotech was granted "PRIME" status by the European Medicines Agency (EMA) for glenzocimab in the treatment of stroke. This designation will allow the company to strengthen its interactions and obtain early dialogues with regulatory authorities.

Acticor Biotech is supported by a panel of European and international investors (Karista, Go Capital, Newton Biocapital, CMS Medical Venture Investment (HK) Limited, A&B (HK) Limited, Mirae Asset Capital, Anaxago, Primer Capital, Mediolanum farmaceutici and the Armesa foundation). Acticor Biotech is listed on Euronext Growth Paris since November 2021 (ISIN: FR0014005OJ5 – ALACT).

For more information, visit: www.acticor-biotech.com

Buy Side Sell Side Number of executions Number of shares Traded volume in EUR Number of executions Number of shares Traded volume in EUR Total

830

77379

503,913.08

868

105591

724,650.10

03/01/2022

5

154

705.32

3

558

2,577.96

04/01/2022

-

-

-

3

130

611.00

05/01/2022

-

-

-

9

390

1,856.40

06/01/2022

1

1

4.70

-

-

-

07/01/2022

1

116

545.20

1

107

513.60

10/01/2022

-

-

-

3

273

1,310.40

11/01/2022

-

-

-

3

23

110.40

12/01/2022

-

-

-

1

477

2,289.60

13/01/2022

-

-

-

19

2400

12,048.00

14/01/2022

-

-

-

18

2436

13,860.84

17/01/2022

-

-

-

21

1263

7,830.60

18/01/2022

-

-

-

25

4702

31,973.60

19/01/2022

-

-

-

3

800

5,520.00

20/01/2022

3

1000

6,800.00

-

-

-

21/01/2022

10

801

5,126.40

1

1

6.50

24/01/2022

8

1700

10,234.00

-

-

-

25/01/2022

12

1492

8,847.56

-

-

-

26/01/2022

7

608

3,496.00

-

-

-

27/01/2022

-

-

-

2

40

236.00

28/01/2022

13

633

3,690.39

-

-

-

31/01/2022

3

167

968.60

1

60

354.00

01/02/2022

4

92

539.12

5

896

5,376.00

02/02/2022

5

401

2,438.08

6

1056

6,504.96

03/02/2022

2

709

4,211.46

2

350

2,205.00

04/02/2022

4

300

1,830.00

-

-

-

07/02/2022

5

567

3,453.03

-

-

-

08/02/2022

7

490

2,959.60

1

1

6.06

09/02/2022

6

670

4,053.50

-

-

-

10/02/2022

6

210

1,264.20

1

1

6.04

11/02/2022

4

200

1,204.00

3

148

896.88

14/02/2022

4

326

1,939.70

1

1

6.02

15/02/2022

5

499

2,919.15

1

1

5.90

16/02/2022

2

46

266.80

-

-

-

17/02/2022

4

401

2,325.80

1

1

5.80

18/02/2022

9

595

3,433.15

1

1

5.80

21/02/2022

3

306

1,744.20

-

-

-

22/02/2022

3

400

2,240.00

4

315

1,795.50

23/02/2022

1

25

141.00

10

1285

7,388.75

24/02/2022

4

1700

9,639.00

1

500

2,870.00

25/02/2022

2

309

1,761.30

3

481

2,760.94

28/02/2022

-

-

-

13

2217

12,969.45

01/03/2022

-

-

-

13

3854

24,241.66

02/03/2022

-

-

-

11

4000

28,960.00

04/03/2022

-

-

-

9

3500

28,000.00

07/03/2022

-

-

-

9

2000

16,700.00

08/03/2022

-

-

-

7

900

7,596.00

09/03/2022

7

600

4,920.00

-

-

-

10/03/2022

7

900

7,083.00

5

500

4,150.00

11/03/2022

1

1

8.00

8

800

6,480.00

14/03/2022

21

3250

24,472.50

-

-

-

15/03/2022

2

500

3,625.00

8

1250

9,162.50

16/03/2022

-

-

-

1

250

1,825.00

17/03/2022

8

500

3,610.00

1

180

1,305.00

18/03/2022

7

1000

7,030.00

-

-

-

21/03/2022

12

939

6,441.54

1

1

7.10

22/03/2022

8

500

3,400.00

3

200

1,380.00

23/03/2022

5

564

3,722.40

-

-

-

24/03/2022

-

-

-

1

1

6.70

25/03/2022

2

436

2,851.44

2

254

1,701.80

28/03/2022

8

1000

6,490.00

3

102

673.20

29/03/2022

8

652

4,172.80

5

1000

6,480.00

30/03/2022

2

17

108.80

7

1243

8,216.23

31/03/2022

2

250

1,625.00

1

250

1,675.00

01/04/2022

3

558

3,593.52

2

250

1,625.00

04/04/2022

4

400

2,584.00

-

-

-

05/04/2022

-

-

-

7

1251

8,331.66

06/04/2022

2

350

2,334.50

1

1

6.80

07/04/2022

2

450

2,952.00

1

149

983.40

08/04/2022

5

320

2,076.80

2

11

72.60

11/04/2022

3

499

3,318.35

10

1840

12,843.20

12/04/2022

4

266

1,806.14

1

1

6.80

13/04/2022

2

235

1,574.50

-

-

-

14/04/2022

4

166

1,112.20

2

11

74.80

19/04/2022

4

500

3,625.00

17

3455

26,707.15

20/04/2022

8

1250

9,325.00

5

1000

7,880.00

21/04/2022

4

371

2,808.47

11

1945

15,209.90

22/04/2022

14

755

5,911.65

2

500

3,975.00

25/04/2022

11

704

5,498.24

-

-

-

26/04/2022

4

267

2,053.23

4

750

5,947.50

27/04/2022

4

233

1,770.80

-

-

-

28/04/2022

3

80

600.00

1

1

7.70

29/04/2022

3

50

370.00

4

751

5,782.70

02/05/2022

-

-

-

13

2100

16,884.00

03/05/2022

-

-

-

2

123

1,008.60

04/05/2022

5

261

2,088.00

9

1378

11,451.18

05/05/2022

5

395

3,160.00

1

250

2,050.00

06/05/2022

10

1041

8,244.72

1

1

8.20

09/05/2022

2

210

1,617.00

3

266

2,101.40

10/05/2022

2

126

970.20

5

228

1,778.40

11/05/2022

-

-

-

3

250

1,950.00

12/05/2022

4

251

1,932.70

1

1

7.72

13/05/2022

4

250

1,925.00

1

250

1,950.00

16/05/2022

10

1200

8,892.00

3

500

3,825.00

17/05/2022

8

752

5,640.00

1

1

7.72

18/05/2022

1

250

1,825.00

1

1

7.60

19/05/2022

2

250

1,825.00

-

-

-

20/05/2022

16

2250

15,682.50

3

251

1,807.20

23/05/2022

5

250

1,700.00

6

162

1,117.80

24/05/2022

2

16

107.20

2

251

1,706.80

25/05/2022

-

-

-

6

1000

7,050.00

26/05/2022

-

-

-

5

250

1,775.00

27/05/2022

1

1

7.10

1

1

7.10

30/05/2022

6

500

3,525.00

2

101

727.20

31/05/2022

2

56

392.00

3

301

2,143.12

01/06/2022

6

696

4,844.16

1

1

7.02

02/06/2022

2

485

3,273.75

2

162

1,117.80

03/06/2022

2

500

3,400.00

8

888

6,224.88

06/06/2022

1

15

105.00

2

30

213.00

07/06/2022

6

245

1,715.00

1

1

7.08

08/06/2022

7

742

5,119.80

1

1

7.04

09/06/2022

1

250

1,700.00

-

-

-

10/06/2022

2

250

1,700.00

1

10

69.00

13/06/2022

1

250

1,675.00

2

16

108.96

14/06/2022

6

251

1,681.70

3

336

2,284.80

15/06/2022

5

251

1,681.70

4

20

136.00

16/06/2022

1

15

100.50

-

-

-

17/06/2022

2

31

207.70

-

-

-

20/06/2022

2

17

113.90

6

861

5,975.34

21/06/2022

4

251

1,731.90

2

10

70.00

22/06/2022

3

17

115.60

2

2

13.78

23/06/2022

2

17

115.60

5

170

1,173.00

24/06/2022

4

19

129.20

3

12

82.80

27/06/2022

1

15

102.00

2

68

469.20

28/06/2022

1

1

6.88

1

1

6.88

29/06/2022

3

185

1,258.00

1

1

6.84

30/06/2022

-

-

-

4

250

1,725.00

01/07/2022

1

159

1,081.20

2

11

76.01

04/07/2022

4

341

2,318.80

-

-

-

05/07/2022

1

15

102.00

2

11

75.90

06/07/2022

3

235

1,598.00

1

1

6.90

07/07/2022

7

415

2,813.70

1

1

6.82

08/07/2022

20

2781

17,742.78

5

619

4,073.02

11/07/2022

2

500

3,025.00

5

500

3,075.00

12/07/2022

4

501

3,056.10

1

1

6.26

13/07/2022

3

500

3,025.00

1

1

6.20

14/07/2022

3

500

3,000.00

-

-

-

15/07/2022

4

251

1,506.00

1

1

6.06

18/07/2022

4

251

1,506.00

1

1

6.02

19/07/2022

-

-

-

1

1

6.10

20/07/2022

1

1

5.98

2

168

1,008.00

21/07/2022

6

321

1,916.37

2

83

498.00

22/07/2022

-

-

-

3

249

1,518.90

25/07/2022

2

251

1,506.00

1

1

6.10

26/07/2022

9

718

4,494.68

7

1381

9,004.12

27/07/2022

22

1712

10,186.40

3

265

1,698.65

28/07/2022

10

500

2,925.00

2

2

12.20

29/07/2022

-

-

-

2

102

612.00

01/08/2022

6

1500

8,550.00

3

251

1,455.80

02/08/2022

1

1

5.76

6

343

1,996.26

04/08/2022

1

1

5.72

3

35

205.10

05/08/2022

-

-

-

1

1

5.86

08/08/2022

11

500

2,925.00

2

250

1,500.00

09/08/2022

1

1

5.80

2

7

41.23

10/08/2022

1

1

5.80

1

1

5.80

11/08/2022

1

250

1,425.00

2

101

585.80

12/08/2022

1

1

5.78

3

394

2,308.84

16/08/2022

7

251

1,455.80

1

1

5.88

17/08/2022

-

-

-

1

1

5.90

18/08/2022

2

250

1,450.00

2

498

2,963.10

19/08/2022

-

-

-

2

250

1,475.00

22/08/2022

7

250

1,450.00

-

-

-

25/08/2022

1

1

5.72

1

1

5.72

26/08/2022

1

1

5.78

1

1

5.78

29/08/2022

7

1691

9,469.60

3

46

262.20

30/08/2022

-

-

-

1

1

5.70

31/08/2022

4

59

330.40

1

1

5.68

01/09/2022

-

-

-

4

145

826.50

02/09/2022

-

-

-

2

59

339.84

05/09/2022

1

1

5.74

1

1

5.74

06/09/2022

7

1500

8,235.00

1

5

28.50

07/09/2022

1

100

540.00

6

119

654.50

08/09/2022

5

473

2,516.36

2

30

165.00

09/09/2022

1

1

5.38

3

38

205.20

12/09/2022

-

-

-

5

809

4,554.67

13/09/2022

-

-

-

1

250

1,425.00

14/09/2022

-

-

-

2

250

1,450.00

15/09/2022

1

1

5.78

1

1

5.78

16/09/2022

1

1

5.76

1

1

5.76

19/09/2022

2

41

234.52

2

250

1,450.00

20/09/2022

1

1

5.76

1

1

5.76

21/09/2022

5

284

1,627.32

1

1

5.76

22/09/2022

1

1

5.72

1

1

5.72

23/09/2022

11

1546

8,363.86

2

15

85.50

26/09/2022

8

668

3,547.08

-

-

-

27/09/2022

3

501

2,655.30

4

544

2,970.24

28/09/2022

2

280

1,481.20

1

1

5.40

29/09/2022

-

-

-

5

162

874.80

30/09/2022

-

-

-

4

87

469.80

03/10/2022

-

-

-

4

221

1,215.50

04/10/2022

1

1

5.48

3

7

38.50

05/10/2022

-

-

-

1

23

126.50

06/10/2022

1

1

5.50

1

1

5.50

07/10/2022

4

251

1,380.50

2

51

285.60

10/10/2022

-

-

-

3

290

1,597.90

11/10/2022

1

1

5.58

1

1

5.58

12/10/2022

-

-

-

3

328

1,856.48

13/10/2022

2

251

1,405.60

3

22

125.40

14/10/2022

1

1

5.62

1

1

5.62

17/10/2022

4

526

2,893.00

-

-

-

18/10/2022

2

438

2,382.72

3

22

123.20

19/10/2022

-

-

-

5

189

1,039.50

20/10/2022

1

1

5.46

5

15

82.50

21/10/2022

1

18

99.00

5

73

408.80

24/10/2022

1

100

560.00

5

454

2,569.64

25/10/2022

1

1

5.62

2

251

1,430.70

26/10/2022

1

45

256.50

1

250

1,450.00

27/10/2022

1

200

1,140.00

2

250

1,450.00

28/10/2022

4

358

2,029.86

9

1813

10,769.22

31/10/2022

2

427

2,502.22

-

-

-

01/11/2022

2

19

114.38

-

-

-

02/11/2022

7

821

4,958.84

1

1

6.14

03/11/2022

5

104

624.00

1

200

1,220.00

04/11/2022

3

251

1,516.04

1

1

6.08

07/11/2022

5

119

714.00

-

-

-

08/11/2022

3

54

324.00

1

1

6.02

09/11/2022

1

1

6.04

4

11

66.99

10/11/2022

4

301

1,799.98

1

1

6.10

11/11/2022

2

76

448.40

1

1

5.92

14/11/2022

2

23

135.70

1

100

600.00

15/11/2022

3

25

147.50

1

1

5.94

16/11/2022

5

79

466.10

1

1

5.94

17/11/2022

4

50

295.00

3

401

2,430.06

18/11/2022

-

-

-

8

1420

9,002.80

21/11/2022

-

-

-

9

1250

8,075.00

22/11/2022

-

-

-

7

1135

7,491.00

23/11/2022

-

-

-

18

2789

19,523.00

24/11/2022

-

-

-

18

2386

17,036.04

25/11/2022

-

-

-

9

1264

9,164.00

28/11/2022

-

-

-

15

2722

20,033.92

29/11/2022

2

324

2,326.32

19

2341

17,370.22

30/11/2022

3

250

1,800.00

-

-

-

01/12/2022

7

927

6,433.38

4

292

2,058.60

02/12/2022

2

41

287.82

16

2386

16,797.44

05/12/2022

3

175

1,232.00

11

1824

13,132.80

06/12/2022

-

-

-

19

2249

16,777.54

07/12/2022

-

-

-

4

633

4,747.50

08/12/2022

-

-

-

8

854

6,507.48

09/12/2022

-

-

-

5

884

6,656.52

12/12/2022

2

250

1,850.00

-

-

-

13/12/2022

8

353

2,601.61

-

-

-

14/12/2022

6

898

6,438.66

1

1

7.32

15/12/2022

3

66

466.62

1

1

7.08

16/12/2022

11

1301

9,067.97

3

501

3,501.99

19/12/2022

2

53

365.17

6

500

3,495.00

20/12/2022

6

34

235.28

3

750

5,287.50

21/12/2022

1

1

7.08

1

1

7.08

22/12/2022

4

495

3,474.90

1

1

7.04

23/12/2022

-

-

-

6

503

3,556.21

27/12/2022

7

1000

7,350.00

14

1803

13,360.23

28/12/2022

1

1

7.10

-

-

-

29/12/2022

4

499

3,517.95

1

85

603.50

30/12/2022

2

16

111.68

3

62

437.72

 

View source version on businesswire.com: https://www.businesswire.com/news/home/20230106005290/en/

ACTICOR BIOTECH Gilles AVENARD, MD CEO and Founder gilles.avenard@acticor-biotech.com T. : +33 (0)6 76 23 38 13

Sophie BINAY, PhD General Manager and CSO Sophie.binay@acticor-biotech.com T. : +33 (0)6 76 23 38 13

NewCap Mathilde BOHIN / Quentin MASSÉ Investor Relations acticor@newcap.eu T. : +33 (0)1 44 71 94 95

NewCap Arthur ROUILLÉ Media Relations acticor@newcap.eu T. : +33 (0)1 44 71 00 15